Electric Literature of 60-56-0, These common heterocyclic compound, 60-56-0, name is 1-Methyl-1H-imidazole-2(3H)-thione, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
General procedure: A mixture of N-(naphthalen-1-yl)propanamide (1.50 mmol,0.35 g) and mercapto derivatives (1.50 mmol) were dissolved in acetone (15 ml). For catalytic purposes, potassium carbonate(1.50 mmol, 0.21 g) was added to the round bottom flask. After 2 h, the reaction was monitored by TLC. Ultimately the solvent was vanished to dryness, the solid was filtered and washed with water. The final products were recrystallized from ethanol.
The synthetic route of 60-56-0 has been constantly updated, and we look forward to future research findings.
Reference:
Article; Evren, Asaf E.; Yurttas, Leyla; Y?lmaz-Cankilic, Meral; Phosphorus, Sulfur and Silicon and the Related Elements; vol. 195; 2; (2020); p. 158 – 164;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem