Synthetic Route of 29914-81-6, A common heterocyclic compound, 29914-81-6, name is 1,3-Bis(1H-benzo[d]imidazol-2-yl)benzene, molecular formula is C20H14N4, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
c. Add 2.56 mmol of 1,14.3 mmol KOH and 2 mL of 1-iodo-n-hexane were dissolved in 30 mL of acetonitrile and refluxed for 24 hours. The solvent was removed to obtain a brown oil, which was dissolved in chloroform. Distilled water was extracted and washed 9-10 times, and the filtrate was taken to obtain a brown solution. Concentrated to 3 ~ 5mL, using 100 ~ 200 mesh silica gel as stationary phase, ethyl acetate was used as the eluent for column chromatography. The Rf of the product was 0.7 to 0.8. bisbenzimidazole phenyl complex 2 was obtained (yellow-white solid, yield 89%).
The synthetic route of 29914-81-6 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Guangzhou Yuxin Intelligent Science And Technology Institute Co., Ltd.; Xi Yanan; Hu Shujin; (17 pag.)CN110590853; (2019); A;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem