In an article, author is Kucukbay, H, once mentioned the application of 288-32-4, COA of Formula: C3H4N2, Name is 1H-Imidazole, molecular formula is C3H4N2, molecular weight is 68.0773, MDL number is MFCD00005183, category is imidazoles-derivatives. Now introduce a scientific discovery about this category.
Synthesis and antimicrobial activity of substituted benzimidazole, benzothiazole and imidazole derivatives
New benzimidazole, benzothiazole and imidazole derivatives were synthesized by reacting electron-rich olefins (5, 23 and 29) with appropriate reagents The compounds synthesized were identified by H-1, C-13-NMR, FT-IR and mass spectroscopic techniques and micro analysis. All new and related compounds were evaluated for their in vitro antimicrobial activity against different bacteria. The compounds 17, 18, 19, 20, 21, 22 and 24 were found very effective to inhibit the growth of Enterococcus faecalis (ATCC 29212) and Staphylococcus aureus (ATCC 29213) at minimum inhibitory concentrations (MICs) of 25, 25, 12.5, 50, 25, 50 and 50 mu g/ml, respectively. The compounds 4, 10a, 10c, 16, 25, 26 and 31 were significantly effective against Enterococcus faecalis (ATCC 29212) and Staphylococcus aureus (ATCC 29213) with MIC values of 100-200 mu g/ml. None of the compounds proved to be effective against Escherichia coli (ATCC 25922) and Pseudomonas aeruginosa (ATCC 27853) in the concentrations studied.
If you are interested in 288-32-4, you can contact me at any time and look forward to more communication. COA of Formula: C3H4N2.