In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 85692-37-1 as follows. Formula: C6H8N2O
1-Methyl-2-acetylimidazole (1.8 g, 16.36 mmol) and LiOH (392 mg, 16.36 mmol) were stirred in MeOH (100 mL) before methyl 4-formylbenzoate (2.6 g, 16.36 mmol) was added. After 30 min a thick yellow precipitate was formed. The precipitate was filtered and dried under vacuum to yield 2c as a yellow solid (63%).
According to the analysis of related databases, 85692-37-1, the application of this compound in the production field has become more and more popular.
Reference:
Article; Jacob, Nicholas T.; Miranda, Pedro O.; Shirey, Ryan J.; Gautam, Ritika; Zhou, Bin; de Orbe Izquierdo, M. Elena; Hixon, Mark S.; Hart, Jonathan R.; Ueno, Lynn; Vogt, Peter K.; Janda, Kim D.; Bioorganic and Medicinal Chemistry; vol. 26; 14; (2018); p. 4234 – 4239;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem