Some common heterocyclic compound, 7098-07-9, name is 1-Ethyl-1H-imidazole, molecular formula is C5H8N2, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route. Application In Synthesis of 1-Ethyl-1H-imidazole
Step 1: 341 parts of 1-ethylimidazole (manufactured by Tokyo Chemical Industry Co., Ltd.), 319 parts of dimethyl carbonate (manufactured by Tokyo Chemical Industry Co., Ltd.) and 340 parts of methanol (Tokyo Chemical Industry Co., Ltd.) were charged in a stainless steel autoclave equipped with a reflux condenser, And dissolved. Then, the temperature was raised to 140 ° C. The reaction was carried out at a pressure of 0.8 MPa for 30 hours. 1 H-NMR analysis of the reaction product revealed that 1-ethyl-3-methylimidazolium monomethyl carbonate was formed.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 7098-07-9, its application will become more common.
Reference:
Patent; SANYO CHEMICAL INDUSTRIES LIMITED; SATOU, YOSHIMI; MURATA, SHINICHI; SEIKE, HIDEO; (20 pag.)JP5848690; (2016); B2;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem