Adding a certain compound to certain chemical reactions, such as: 17325-26-7, name is Methyl 1H-imidazole-5-carboxylate, belongs to imidazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 17325-26-7, SDS of cas: 17325-26-7
For methyl 1-tritylimidazole-4-carboxylate (6), trityl chloride(1.77 g, 6.35 mmol) was first stirred into a solution of 5 (0.80 g,6.3 mmol) in DMF (20 mL) under N2. NEt3 (0.98 mL, 7.0 mmol) wasthen added, and the mixture stirred for 16 h at r.t. before being pouredover ice; the cold mixture was then filtered and the isolated solid waswashed with H2O (2 × 5 mL), and then dried in vacuo at r.t. for 24 h.Yield: 2.01 g (86%). 1H NMR (CDCl3): delta 7.65 (s, 1H, H5-Im), 7.52 (s, 1H,H2-Im), 7.03-7.36 (m, 15H, Ph3C), 2.42 (s, 3H, CH3-Im). ESI-MS: 369(M+), 243 (CPh3). Anal. Calcd. for C24H20N2O2: C, 78.24; H, 5.47; N,7.60. Found: C, 78.35; H, 5.6; N, 7.4.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, Methyl 1H-imidazole-5-carboxylate, other downstream synthetic routes, hurry up and to see.
Reference:
Article; Kennedy, David C.; James, Brian R.; Inorganic Chemistry Communications; vol. 78; (2017); p. 32 – 36;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem