Related Products of 1116-98-9. Aromatic compounds can be divided into two categories: single heterocycles and fused heterocycles. Compound: tert-Butyl 2-cyanoacetate, is researched, Molecular C7H11NO2, CAS is 1116-98-9, about Activated 2-methylidene-1,3-thiazolidin-4-ones in a promising approach to the synthesis of polyfunctional thiazolo[3,2-c]pyrimidines. Author is Litvinchuk, Mariia B.; Bentya, Anton V.; Rusanov, Eduard B.; Vovk, Mykhailo V..
A preparatively convenient and efficient synthetic route to new 5H-[1,3]thiazolo[3,2-c]pyrimidine derivatives I (R = cyclopropyl, tert-Bu, methoxy, benzyloxy, tert-butyloxy, Ar = Ph, 3-bromophenyl, 4-chlorophenyl, 4-fluorophenyl) is described that involves the cyclocondensation of acyl or alkoxycarbonyl α-functionalized 2-methylidene-1,3-thiazolidin-4-ones II with 1-chlorobenzyl isocyanates ArCH(Cl)NCO. The optimal reaction conditions, viz., heating reagents in toluene in the absence of an organic base, afford the target products in 48-74% yields. Some tert-Bu 2-(4-oxo-1,3-thiazolidin-2-ylidene)ethanoates produce, along with the desired tert-Bu [1,3]thiazolo[3,2-c]pyrimidine-8-carboxylates I (R = tert-BuO, Ar = Ph, 3-bromophenyl, 4-chlorophenyl), the corresponding 8-carboxylic acids III in 18-21% yields. A reliable structural determination of all the synthesized compounds has been performed by elemental anal. and a number of spectroscopic methods (1H and 13C NMR, HPLC/MS, and FT-IR) as well as by X-ray diffraction anal.
As far as I know, this compound(1116-98-9)Related Products of 1116-98-9 can be applied in many ways, which is helpful for the development of experiments. Therefore many people are doing relevant researches.
Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem