Related Products of 16961-25-4. The protonation of heteroatoms in aromatic heterocycles can be divided into two categories: lone pairs of electrons are in the aromatic ring conjugated system; and lone pairs of electrons do not participate. Compound: Hydrogen tetrachloroaurate(III) trihydrate, is researched, Molecular AuCl4H7O3, CAS is 16961-25-4, about Tuning stable noble metal nanoparticles dispersions to moderate their interaction with model membranes. Author is William, Nicola; Bamidoro, Faith; Beales, Paul A.; Drummond-Brydson, Rik; Hondow, Nicole; Key, Sarah; Kulak, Alexander; Walsh, Aidan Charles; Winter, Sophia; Nelson, Laurence Andrew.
The properties of stable gold (Au) nanoparticle dispersions can be tuned to alter their activity towards biomembrane models. Au nanoparticle coating techniques together with rapid electrochem. screens of a phospholipid layer on fabricated mercury (Hg) on platinum (Pt) electrode have been used to moderate the phospholipid layer activity of Au nanoparticle dispersions. Screening results for Au nanoparticle dispersions were intercalibrated with phospholipid large unilamellar vesicle (LUV) interactions using a carboxyfluorescein (CF) leakage assay. All nanoparticle dispersions were characterised for size, by dynamic light scattering (DLS) and transmission electron microscopy (TEM). Com. and high quality home synthesized Au nanoparticle dispersions are phospholipid monolayer active whereas Ag nanoparticle dispersions are not. If Au nanoparticles are coated with a thin layer of Ag then the particle/lipid interaction is suppressed. The electrochem. assays of the lipid layer activity of Au nanoparticle dispersions align with LUV leakage assays of the same. Au nanoparticles of decreasing size and increasing dispersion concentration showed a stronger phospholipid monolayer/bilayer interaction. Treating Au nanoparticles with cell culture medium and incubation of Au nanoparticle dispersions in phosphate buffered saline (PBS) solutions removes their phospholipid layer interaction.
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Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem