In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Economical and eco-friendly method for the reduction of heterocyclics possessing α,β-unsaturated acid systems using novel reduction method, published in 2014, which mentions a compound: 3724-19-4, mainly applied to aldehyde heteroaryl malonic acid condensation; acrylic acid heterocyclic preparation reduction palladium catalyst; propionic acid heterocyclic preparation green chem, Safety of 3-Pyridinepropionic acid.
Reduction of hetero aryl acrylic acid RHC=CHCO2H [R = 2-furanyl, 3-pyrazinyl, 3-quinolinyl] to hetero aryl propionic acids RCH2CH2CO2H was achieved using hydrazine hydrate and an oxidizing agent and yields were reported. Moreover, reduction of hetero aryl acrylic acids RHC = CHCO2H was also carried out using Palladium charcoal method and the yields of both the methods were compared. It was observed that though the yields were slightly less in hydrazine reduction method, the method appeared to be economical, eco-friendly with operational simplicity, reasonable yields and easy workup procedures, which may be applied to large scale synthesis.
This literature about this compound(3724-19-4)Safety of 3-Pyridinepropionic acidhas given us a lot of inspiration, and I hope that the research on this compound(3-Pyridinepropionic acid) can be further advanced. Maybe we can get more compounds in a similar way.
Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem