Ohba, Masashi; Mukaihira, Takafumi; Fujii, Tozo published the artcile< Synthesis of 5-arylthio-3-methyl-L-histidine, a model for the starfish alkaloid imbricatine>, Electric Literature of 1003-21-0, the main research area is histidine arylthiomethyl; imbricatine model synthesis.
Syntheses of 3-methyl-5-phenylthio-L-histidine (I, R = Ph) and 3-methyl-5-(1-naphthyl)thio-L-histidine ( R = 1-naphthyl), selected as models for the asteroid alkaloid imbricatine (II), have now become feasible through a 10-step route starting from 4(5)-bromoimidazole. The key steps involve replacement of the 4-bromo group by an arylthio group in the aldehyde III and construction of the L-alanine moiety in the chlorides IV by the “”bis-lactim ether”” method.
Heterocycles published new progress about 1003-21-0. 1003-21-0 belongs to class imidazoles-derivatives, and the molecular formula is C4H5BrN2, Electric Literature of 1003-21-0.
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem