The author of 《Dioxothietanylation of heterocycles 2*. Imidazoles and benzimidazoles》 were Makarova, Nadezhda N.; Klen, Elena E.; Khaliullin, Ferkat A.. And the article was published in Chemistry of Heterocyclic Compounds (New York, NY, United States) in 2019. Synthetic Route of C7H5ClN2 The author mentioned the following in the article:
The 1-(1,1-dioxidothietan-3-yl)-1H-benzimidazoles I (R = H, Cl, CH3, C6H5CH2, CH3S, CH3CH2S) and 1-(1,1-dioxidothietan-3-yl)-1H-imidazoles II (R1 = H, CH3; R2 = H, NO2) were synthesized in the reaction of 3,5-dibromo-1-(1,1-dioxidothietan-3-yl)-1H-1,2,4-triazole with the sodium salts of benzimidazoles III and imidazoles IV. The reaction involves addition of azoles to thiete 1,1-dioxide formed in situ, which acts as a Michael acceptor. The effect of pKa values of benzimidazoles III and imidazoles IV on their reactivity is shown. The results came from multiple reactions, including the reaction of 2-Chloro-1H-benzo[d]imidazole(cas: 4857-06-1Synthetic Route of C7H5ClN2)
2-Chloro-1H-benzo[d]imidazole(cas: 4857-06-1) is an analog of benzimidazole that has been synthesized by Langmuir adsorption isotherm. It is a white crystalline solid that can be dissolved in water and hydrochloric acid. 2-Chloro-1H-benzo[d]imidazole inhibits the growth of herpes simplex virus by acting as a competitive inhibitor for the viral enzyme thymidine kinase, which catalyzes the conversion of thymine to thymidine.Synthetic Route of C7H5ClN2
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem