Rakhmonova, Dilnoza; Kadirova, Zukhra; Torambetov, Batirbay; Kadirova, Shakhnoza; Ashurov, Jamshid; Shishkina, Svitlana published an article in Acta Crystallographica, Section E: Crystallographic Communications. The title of the article was 《The molecular and crystal structures of 2-(3-hydroxypropyl)benzimidazole and its nitrate salt》.Reference of 3-(1H-Benzo[d]imidazol-2-yl)propan-1-ol The author mentioned the following in the article:
2-(3-Hydroxypropyl)-1H-benzimidazole, C10H12N2O, which has potential biol. activity, can be used as a ligand for complexation with metals. This compound is an electron donor, due to the lone pair of the nitrogen atom in the imidazole ring. This nitrogen atom also acts as a proton acceptor. In the crystalline phase, the nitrate salt, namely, 2-(3-hydroxypropyl)-1H-benzimidazol-3-ium nitrate, C10H13N2O+·NO3-, has been studied. The protonation of the 2-(3-hydroxypropyl)benzimidazole unit results in significant delocalization of the electron d. within the imidazole ring. The salt formation leads to variations in the intermol. interactions, which were studied by anal. of the Hirshfeld surfaces and two-dimensional fingerprint plots.3-(1H-Benzo[d]imidazol-2-yl)propan-1-ol(cas: 2403-66-9Reference of 3-(1H-Benzo[d]imidazol-2-yl)propan-1-ol) was used in this study.
3-(1H-Benzo[d]imidazol-2-yl)propan-1-ol(cas: 2403-66-9) belongs to imidazoles.Imidazole rings are part of unnatural cyclic peptides and are used as ester isosteres in peptidomimetic studies.
However, the application of imidazoles is not limited to the field of peptides and peptidomimetics. Reference of 3-(1H-Benzo[d]imidazol-2-yl)propan-1-ol
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem