Akiyama, Masayasu; Hara, Yukihiro; Tanabe, Minoru published the artcile< Effects of the substituents on the hydrolysis of 4-nitrophenyl acetate catalyzed by 2-substituted imidazoles>, Computed Properties of 36947-69-0, the main research area is hydrolysis kinetics nitrophenyl acetate imidazole; Broensted catalysis nitrophenyl acetate hydrolysis; mechanism hydrolysis nitrophenyl acetate imidazole; LFER hydrolysis nitrophenyl acetate.
A series of 2-alkyl and -(hydroxyalkyl)-substituted imidazoles catalyzed the hydrolysis of 4-nitrophenyl acetate. Activation parameters and D2O solvent isotope effects were determined for some of these imidazoles and showed that a bulky substituent decreased the rate of nucleophilic catalysis for most of the imidazoles. Anal. in terms of the Broensted catalysis law gave an extrapolated rate for each imidazole and indicated the importance of the steric effect relative to the parent compound Catalysis by 2-(1,1-dimethyl-2-hydroxyethyl)imidazole involved partial general base catalysis.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999) published new progress about Bronsted LFER. 36947-69-0 belongs to class imidazoles-derivatives, and the molecular formula is C7H12N2, Computed Properties of 36947-69-0.
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem