Karuvalam, Ranjith P.; Haridas, Karickal R.; Shetty, Suchetha N. published an article in Journal of the Chilean Chemical Society. The title of the article was 《Trimethylsilyl chloride-catalyzed synthesis of substituted benzimidazoles using two phase system under microwave conditions, and their antimicrobial studies》.Recommanded Product: 3-(1H-Benzo[d]imidazol-2-yl)propan-1-ol The author mentioned the following in the article:
A convenient method using Me3SiCl (20 mol %) and microwave-induced technique for the synthesis of various benzimidazole is described. This reduced the reaction time drastically as well as improved the yield when compared to conventional heating. The synthesized compounds were evaluated for their in vitro antibacterial and antifungal activities against four strains each. Some of the compounds indicated very good antimicrobial activity, comparable to the first line standard drugs. The most effective compounds exhibited activity at MIC of 6.25 μg/mL. In the experiment, the researchers used 3-(1H-Benzo[d]imidazol-2-yl)propan-1-ol(cas: 2403-66-9Recommanded Product: 3-(1H-Benzo[d]imidazol-2-yl)propan-1-ol)
3-(1H-Benzo[d]imidazol-2-yl)propan-1-ol(cas: 2403-66-9) belongs to imidazoles.Although other azole heterocycles are ubiquitous in a wide range of biologically active natural products, imidazole rings occur predominantly in the natural amino acid histidine. In addition, imidazole rings are part of unnatural cyclic peptides and are used as ester isosteres in peptidomimetic studies. Recommanded Product: 3-(1H-Benzo[d]imidazol-2-yl)propan-1-ol
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem