Electric Literature of C10H12N2OOn October 20, 2010 ,《Tetra butyl ammonium chloride catalyzed synthesis of substituted benzimidazoles under microwave conditions》 was published in Journal of the Korean Chemical Society. The article was written by Karuvalam, Ranjith. P.; Siji, M.; Divia., N.; Haridas, Karickal. R.. The article contains the following contents:
Tetrabutylammonium chloride (10 mol%) was a useful catalyst for the synthesis of substituted benzimidazoles from o-phenylenediamines with benzoic acids. The method was simple, convenient and the product was isolated with good yield. In addition to this study using 3-(1H-Benzo[d]imidazol-2-yl)propan-1-ol, there are many other studies that have used 3-(1H-Benzo[d]imidazol-2-yl)propan-1-ol(cas: 2403-66-9Electric Literature of C10H12N2O) was used in this study.
3-(1H-Benzo[d]imidazol-2-yl)propan-1-ol(cas: 2403-66-9) belongs to imidazoles.Imidazole rings are also present in imidazole ring alkaloids, which are potential therapeutics for thrombosis, cancer and inflammatory diseases.Electric Literature of C10H12N2O Although other azole heterocycles are ubiquitous in a wide range of biologically active natural products, imidazole rings occur predominantly in the natural amino acid histidine.
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem