The author of 《Acid, silver, and solvent-free gold-catalyzed hydrophenoxylation of internal alkynes》 were Richard, Marcia E.; Fraccica, Daniel V.; Garcia, Kevin J.; Miller, Erica J.; Ciccarelli, Rosa M.; Holahan, Erin C.; Resh, Victoria L.; Shah, Aakash; Findeis, Peter M.; Stockland, Robert A. Jr.. And the article was published in Beilstein Journal of Organic Chemistry in 2013. Application In Synthesis of Chloro{1,3-bis[2,6-bis(1-methylethyl)phenyl]-4,5-dihydroimidazol-2-ylidene}gold(I) The author mentioned the following in the article:
A range of (aryl)gold compounds were synthesized and investigated as single-component catalysts for a hydrophenoxylation of un-activated internal alkynes. Both carbene and phosphine-ligated compounds were screened as part of this work and the most efficient catalysts contained either JohnPhos or IPr/SIPr. Phenols bearing either electron-withdrawing or electron-donating groups were efficiently added using these catalysts. No silver salts, acids, or solvents were needed for the catalysis, and either microwave or conventional heating afforded moderate to excellent yields of the vinyl ethers. The title compounds thus formed included 1-[[(1Z)-1,2-diphenylethenyl]oxy]-4-nitrobenzene (I) and related substances, such as 1-nitro-4-[[(1Z)-1-phenyl-1-hexen-1-yl]oxy]benzene. The synthesis of the target compounds was achieved by a reaction of alkynes, such as 1,2-diphenylethyne, 5-decyne, (1-hexynyl)benzene with phenol derivatives, such as 4-nitrophenol, methylphenol, [1,1′-biphenyl]-4-ol. In the experiment, the researchers used many compounds, for example, Chloro{1,3-bis[2,6-bis(1-methylethyl)phenyl]-4,5-dihydroimidazol-2-ylidene}gold(I)(cas: 852445-84-2Application In Synthesis of Chloro{1,3-bis[2,6-bis(1-methylethyl)phenyl]-4,5-dihydroimidazol-2-ylidene}gold(I))
Chloro{1,3-bis[2,6-bis(1-methylethyl)phenyl]-4,5-dihydroimidazol-2-ylidene}gold(I)(cas: 852445-84-2) belongs to imidazoles.Imidazole rings are part of unnatural cyclic peptides and are used as ester isosteres in peptidomimetic studies.
However, the application of imidazoles is not limited to the field of peptides and peptidomimetics. Application In Synthesis of Chloro{1,3-bis[2,6-bis(1-methylethyl)phenyl]-4,5-dihydroimidazol-2-ylidene}gold(I)
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem