《Ambident Reactivity of Imidazolium Cations as Evidence of the Dynamic Nature of N-Heterocyclic Carbene-Mediated Organocatalysis》 was published in Chemistry – A European Journal in 2020. These research results belong to Galkin, Konstantin I.; Karlinskii, Bogdan Ya.; Kostyukovich, Alexander Yu.; Gordeev, Evgeniy G.; Ananikov, Valentine P.. HPLC of Formula: 141556-45-8 The article mentions the following:
This work reveals ambident nucleophilic reactivity of imidazolium cations towards carbonyl compounds at the C2 or C4 carbene centers depending on the steric properties of the substrates and reaction conditions. Such an adaptive behavior indicates the dynamic nature of organocatalysis proceeding via a covalent interaction of imidazolium carbenes with carbonyl substrates and can be explained by generation of the H-bonded ditopic carbanionic carbenes. In addition to this study using 1,3-Dimesityl-1H-imidazol-3-ium chloride, there are many other studies that have used 1,3-Dimesityl-1H-imidazol-3-ium chloride(cas: 141556-45-8HPLC of Formula: 141556-45-8) was used in this study.
1,3-Dimesityl-1H-imidazol-3-ium chloride(cas: 141556-45-8) is a ligand for arylation of aldehydes and for carbene catalyzed intermolecular arylation of C-H bonds. It is used as a phosphine-free ligand in various metal-catalyzed coupling reactions, often with advantageous results in difficult cases.HPLC of Formula: 141556-45-8
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem