Category: imidazoles-derivativesOn September 30, 1981 ,《The reaction of imidazolidine-2-thione with carbon disulfide》 was published in Journal of the Chemical Society. The article was written by Yokoyama, Masataka; Motozawa, Kosei; Kawamura, Eiichi; Imamoto, Tsuneo. The article contains the following contents:
The reaction of imidazolidine-2-thione (I) with CS2 in the presence of strong bases is reported. E. g., in the presence of NaH (THF/HMPA/DMSO) 64% bis(thioamide) II and 16% tetrahydrodiimidazothiadiazinethione III were formed, whereas reaction of I with CS2 using BuLi, followed by methylation gave 79% carbodithiolate IV. In the experiment, the researchers used many compounds, for example, Methyl 2-(methylthio)-4,5-dihydro-1H-imidazole-1-carboxylate(cas: 60546-77-2Category: imidazoles-derivatives)
Methyl 2-(methylthio)-4,5-dihydro-1H-imidazole-1-carboxylate(cas: 60546-77-2) belongs to imidazoles.Although other azole heterocycles are ubiquitous in a wide range of biologically active natural products, imidazole rings occur predominantly in the natural amino acid histidine. Category: imidazoles-derivatives In addition, imidazole rings are part of unnatural cyclic peptides and are used as ester isosteres in peptidomimetic studies.
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem