Kunz, Peter C.; Klaeui, Wolfgang published the artcile< Zinc and cobalt(II) complexes of tripodal nitrogen ligands of the tris[2-substituted imidazol-4(5)-yl]-phosphane type. Biomimetic hydrolysis of an activated ester>, Category: imidazoles-derivatives, the main research area is tris imidazolyl phosphine ligand preparation zinc cobalt complexation; biomimetic ester hydrolysis zinc enzyme; nitrophenyl pyridine carboxylate hydrolysis kinetics zinc cobalt imidazolylphosphine catalyzed.
Novel tris[2-substituted imidazol-4(5)-yl]phosphane (4-TIPR) ligands 2b (R = Ph) and 2c (R = tBu) were prepared as model ligands for the tris(histidine) motif found in many zinc enzymes. They readily form cobalt and zinc nitrato and chloro complexes in protic solvents. The steric requirements of the substituents R in 4(5)-position of the 4-TIPR ligands (R = iPr (2a), Ph (2b), tBu (2c)) is discussed on the basis of their UV/VIS spectra. Zinc complexes of 2a and 2c were studied due to their ability to promote the hydrolysis of the activated ester 4-nitrophenyl pyridine-2-carboxylate (pNpic).
Collection of Czechoslovak Chemical Communications published new progress about Enzymes Role: BCP (Biochemical Process), BIOL (Biological Study), PROC (Process) (model). 36947-69-0 belongs to class imidazoles-derivatives, and the molecular formula is C7H12N2, Category: imidazoles-derivatives.
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem