Sakamoto, Takao; Kondo, Yoshinori; Suginome, Takashi; Ohba, Setsuya; Yamanaka, Hiroshi published the artcile< Palladium-catalyzed cross-coupling reaction of haloazoles with phenylsulfonylacetonitrile>, COA of Formula: C4H5BrN2, the main research area is palladium catalyzed cross coupling reaction haloazole; condensation haloazole phenylsulfonylacetonitrile; oxazoleacetonitrile phenylsulfonyl; thiazoleacetonitrile phenylsulfonyl; imidazoleacetonitrile phenylsulfonyl.
Condensation of halo-substituted 1,3-azoles (1,3-oxazoles, 1,3-thiazoles and imidazoles), e.g., I (R = Br), with phenylsulfonylacetonitrile under basic conditions was promoted by the catalytic action of tetrakis(triphenylphosphine)palladium(0) to give α-phenylsulfonyl-1,3-azoleacetonitriles, e.g., I (R = PhO2SCHCN). The adaptability of halogen atoms for the cross-coupling reaction was investigated. The reaction of 4-halo-1,2-azoles was also examined
Synthesis published new progress about Cross-coupling reaction. 1003-21-0 belongs to class imidazoles-derivatives, and the molecular formula is C4H5BrN2, COA of Formula: C4H5BrN2.
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem