In 2022,Martynova, Ekaterina A.; Scattolin, Thomas; Cavarzerani, Enrico; Peng, Min; Van Hecke, Kristof; Rizzolio, Flavio; Nolan, Steven P. published an article in Dalton Transactions. The title of the article was 《A simple synthetic entryway into new families of NHC-gold-amido complexes and their in vitro antitumor activity》.Recommanded Product: 4857-06-1 The author mentioned the following in the article:
A simple synthetic pathway to Au-NHC amido complexes is described. Syntheses and isolation of [Au(NHC)(NR1R2)] complexes, bearing various NHC ligands and NH-containing heterocycles under mild conditions are reported. The in vitro anticancer activity of these gold-complexes was investigated on three human cancer cell lines. A number of these show comparable or even better antiproliferative activity than cisplatin. Noteworthy is the non-toxicity of most of the complexes on normal cells. In the experimental materials used by the author, we found 2-Chloro-1H-benzo[d]imidazole(cas: 4857-06-1Recommanded Product: 4857-06-1)
2-Chloro-1H-benzo[d]imidazole(cas: 4857-06-1) is an analog of benzimidazole that has been synthesized by Langmuir adsorption isotherm. It is a white crystalline solid that can be dissolved in water and hydrochloric acid. 2-Chloro-1H-benzo[d]imidazole inhibits the growth of herpes simplex virus by acting as a competitive inhibitor for the viral enzyme thymidine kinase, which catalyzes the conversion of thymine to thymidine.Recommanded Product: 4857-06-1
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem