Imidazole is a heterocyclic compound with a five-membered planar ring. It is amphoteric and highly polar. 10111-08-7, formula is C4H4N2O, Name is 1H-Imidazole-2-carbaldehyde. The pharmacophore of imidazole exists in bioactive compounds including amino acids, plant growth regulators and therapeutic agents. Application of C4H4N2O.
Li, Shengnan;Li, Ying;Yan, Bing research published 《 A turn-on fluorescence sensing strategy for rapid detection of flumequine in water environments using covalent-coordination functionalized MOFs》, the research content is summarized as follows. With the high output and large use of antibiotics in the process of aquaculture, pollution caused by antibiotics in water environments is becoming a thorny problem, and its ecol. risk has aroused widespread concern. In this work, the lanthanide hybrid material Eu@ZIF-90-PA is synthesized by a two-step post synthesis strategy using ZIF-90 with a modifiable group as a parent skeleton. Owing to its luminescence properties and water stability, the lanthanide functionalized material can be utilized as a novel “turn-on” fluorescent probe for quant. detection of flumequine in water environments. Addnl., the probe can not only be reused, but also quickly respond to flumequine within 30 s and the detection limit is 0.24 ppm. Even in the complex river water, the probe still exhibits an obvious luminescence enhancement effect with flumequine, which provides an efficient and convenient method for the detection of flumequine in real water. Finally, the fluorescence enhancement mechanism between flumequine and the probe is further explored.
Application of C4H4N2O, 1H-Imidazole-2-carbaldehyde, also known as 1H-Imidazole-2-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes.
1H-Imidazole-2-carboxaldehyde is a broad-spectrum antimicrobial that has been shown to inhibit the growth of bacteria by interfering with protein synthesis. It binds to the cytosolic protein and receptor molecule, which are involved in the activation of bacterial enzymes. Imidazole-2-carboxaldehyde reacts with anhydrous sodium and copper complex to produce hydrogen bonds, which prevent the formation of the nitrogen atoms necessary for cellular processes. This chemical also has biological properties such as glyoxal, which inhibits bacterial growth by reacting with amino groups on proteins., 10111-08-7.
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem