Month: October 2022

The author of 《Synthesis of a phosphaphenanthrene/benzimidazole-based curing agent and its application in flame-retardant epoxy resin》 were Huo, Siqi; Liu, Zhitian; Li, Chuan; Wang, Xiaolei; Cai, Haopeng; Wang, Jun. And the article was published in Polymer Degradation and Stability in 2019. Computed Properties of C7H7N3 The author mentioned the following in the article:

A flame-retardant curing agent (DTA) for epoxy resin (EP), which was constructed by phosphaphenanthrene and benzimidazole groups, was successfully synthesized via one-pot reaction between 2-aminobenzimidazole, terephthalaldehyde, and 9,10-dihydro-9-oxa-10-phosphaphenanthrene-10-oxide (DOPO). DTA induced the decomposition of EP matrix and promoted the carbonization at high temperature As expected, DTA endowed EP thermoset with excellent flame retardancy and smoke suppression. For instance, EP/DDS/DTA-0.5 sample containing only 0.5 wt% phosphorus passed UL94 V-1 rating and its LOI value increased to 34.2%. In addition, the pk-HRR, av-HRR, THR, TSR, and TSP of EP/DDS/DTA-1.0 sample were decreased by 56.6%, 31.6%, 34.4%, 24.6% and 24.6% in comparison to those of EP/DDS sample. The flame retardant mechanism showed that the decomposition products of DTA played an important role in the formation of a compact and intumescent char layer in condensed phase. Meanwhile, the phosphorus-containing and nitrogen-containing fragments, which was generated by the pyrolysis of DTA, quenched the active free radicals and diluted the fuels in gaseous phase. Therefore, DTA exerted flame retardant effect in condensed and gaseous phases during combustion. In the experiment, the researchers used many compounds, for example, 1H-Benzo[d]imidazol-2-amine(cas: 934-32-7Computed Properties of C7H7N3)

1H-Benzo[d]imidazol-2-amine(cas: 934-32-7) can be used in the hydrolysis of a choline carbonate. It was also used in the synthesis of imidazo[1,2-a]benzimidazoles.Computed Properties of C7H7N3

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

The author of 《Screening of ionic liquids for extraction of flavonoids from heather》 were Drozdz, Paulina; Pyrzynska, Krystyna. And the article was published in Natural Product Research in 2019. Application of 174501-65-6 The author mentioned the following in the article:

Room temperature ionic liquids are novel solvents with the specific properties that makes them of interest for application for extraction for a wide range of compounds In this work extraction efficiency of flavonoids from heather flowers using ionic liquids based on imidazolium cation were evaluated and compared with organic solvents. It was found that the anion of ionic liquid significantly influence the extraction yields. Flavonoid content as well as antioxidant activity based on radical scavenging on 1,1-diphenul-2-pirylhydrazyl radicals and cupric reducing antioxidant capacity increased in the order: [Bmim]PF6 < [Bmim]BF4 < [Bmim]Cl. The obtained extraction yield using [Bmim]Cl were higher than reported for 60% ethanol and Et acetate under similar conditions, thus, may be helpful for better utilization of heather flowers as the potential pharmaceutical and nutraceutical ingredients. In the experimental materials used by the author, we found 3-Butyl-1-methyl-1H-imidazol-3-ium tetrafluoroborate(cas: 174501-65-6Application of 174501-65-6)

3-Butyl-1-methyl-1H-imidazol-3-ium tetrafluoroborate(cas: 174501-65-6) is a member of lonic liquids. A multidisciplinary study on lonic liquids is emerging, including chemistry, materials science, chemical engineering, and environmental science. More specifically, some important fundamental viewpoints are now different from the original concepts, as insights into the nature of lonic liquids become deeper. For example, the physicochemical properties of lonic liquids are now recognized as ranging broadly from the oft quoted “nonvolatile, non-flammable, and air and water stable” to those that are distinctly volatile, flammable, and unstable. Application of 174501-65-6

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

The author of 《Influence of Charge Scaling on the Solvation Properties of Ionic Liquid Solutions》 were Cui, Kai; Yethiraj, Arun; Schmidt, J. R.. And the article was published in Journal of Physical Chemistry B in 2019. Computed Properties of C8H15BF4N2 The author mentioned the following in the article:

Scaled-charge force fields (FFs) are widely employed in the simulation of neat ionic liquids (ILs), where the charges on the ions are empirically scaled to approx. account for electronic polarization and/or charge transfer. Such charge scaling has been found to yield significant improvement in liquid-state thermodn. and dynamic properties (when compared to experiment). However, the mean field approximation inherent in charge scaling becomes suspect when applied to IL mixtures or solutions In this work, we simulate solutions of IL with various nonpolar and polar gas solutes and compare results of charge-scaled and polarizable FFs to experiment Our results demonstrate that scaling of the Coulomb interaction inherent in scaled-charge FFs leads to an underestimation of the solute-solvent electrostatic interaction and thus also the enthalpy and free energy of solvation; this effect is particularly pronounced for polar solutes. In some cases, we find that this artificial reduction in the solute-solvent interaction can also alter the apparent phase behavior of the resulting solution Overall, the totality of our results suggests that explicit polarization (rather than charge scaling) is likely necessary to provide high transferability to both neat IL and IL mixtures and solutions3-Butyl-1-methyl-1H-imidazol-3-ium tetrafluoroborate(cas: 174501-65-6Computed Properties of C8H15BF4N2) was used in this study.

3-Butyl-1-methyl-1H-imidazol-3-ium tetrafluoroborate(cas: 174501-65-6) is a member of lonic liquids. Actually, lonic liquids as innovative fluids have received wide attention only during the past two decades. The number of SCI papers published on lonic liquids has exponentially increased from a few in 1996 to >5000 in 2016, exceeding the annual growth rates of other popular scientific areas. Computed Properties of C8H15BF4N2

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

The author of 《Incorporation of an ionic liquid into a midblock-sulfonated multiblock polymer for CO2 capture》 were Dai, Zhongde; Ansaloni, Luca; Ryan, Justin J.; Spontak, Richard J.; Deng, Liyuan. And the article was published in Journal of Membrane Science in 2019. Computed Properties of C8H15BF4N2 The author mentioned the following in the article:

In the present work, hybrid block ionomer/ionic liquid (IL) membranes containing up to 40 wt% IL are prepared by incorporating 1-butyl-3-methylimidazolium tetrafluoroborate ([Bmim][BF4]) into a midblock-sulfonated pentablock polymer (Nexar) that behaves as a thermoplastic elastomer. Various anal. techniques, including thermogravimetric anal. (TGA), Fourier-transform IR (FTIR) spectroscopy, small-angle X-ray scattering (SAXS), and water sorption have been employed to characterize the resultant membrane materials. Single- and mixed-gas permeation tests have been performed at different relative humidity conditions to evaluate membrane gas-separation performance and interrogate the mol. transport of CO2 through these membranes. Addition of IL to Nexar systematically enhances CO2 permeability through membranes in the dry state. Introduction of water vapor into the gas feed further promotes CO2 transport, yielding a maximum permeability of 194 Barrers and a maximum CO2/N2 selectivity of 128 under different test conditions. These results confirm that humidified Nexar/IL hybrid membranes constitute promising candidates for the selective removal, and subsequent capture, of CO2 from mixed gas streams to reduce the environmental contamination largely responsible for global climate change. In the experiment, the researchers used many compounds, for example, 3-Butyl-1-methyl-1H-imidazol-3-ium tetrafluoroborate(cas: 174501-65-6Computed Properties of C8H15BF4N2)

3-Butyl-1-methyl-1H-imidazol-3-ium tetrafluoroborate(cas: 174501-65-6) is a member of lonic liquids. Actually, lonic liquids as innovative fluids have received wide attention only during the past two decades. The number of SCI papers published on lonic liquids has exponentially increased from a few in 1996 to >5000 in 2016, exceeding the annual growth rates of other popular scientific areas. Computed Properties of C8H15BF4N2

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

The author of 《Planar perovskite solar cells with long-term stability using ionic liquid additives》 were Bai, Sai; Da, Peimei; Li, Cheng; Wang, Zhiping; Yuan, Zhongcheng; Fu, Fan; Kawecki, Maciej; Liu, Xianjie; Sakai, Nobuya; Wang, Jacob Tse-Wei; Huettner, Sven; Buecheler, Stephan; Fahlman, Mats; Gao, Feng; Snaith, Henry J.. And the article was published in Nature (London, United Kingdom) in 2019. Recommanded Product: 3-Butyl-1-methyl-1H-imidazol-3-ium tetrafluoroborate The author mentioned the following in the article:

Solar cells based on metal halide perovskites are one of the most promising photovoltaic technologies1-4. Over the past few years, the long-term operational stability of such devices has been greatly improved by tuning the composition of the perovskites5-9, optimizing the interfaces within the device structures10-13, and using new encapsulation techniques14,15. However, further improvements are required in order to deliver a longer-lasting technol. Ion migration in the perovskite active layer-especially under illumination and heat-is arguably the most difficult aspect to mitigate16-18. Here we incorporate ionic liquids into the perovskite film and thence into pos.-intrinsic-neg. photovoltaic devices, increasing the device efficiency and markedly improving the long-term device stability. Specifically, we observe a degradation in performance of only around five per cent for the most stable encapsulated device under continuous simulated full-spectrum sunlight for more than 1,800 h at 70 to 75°C, and estimate that the time required for the device to drop to eighty per cent of its peak performance is about 5,200 h. Our demonstration of long-term operational, stable solar cells under intense conditions is a key step towards a reliable perovskite photovoltaic technol. In the experiment, the researchers used 3-Butyl-1-methyl-1H-imidazol-3-ium tetrafluoroborate(cas: 174501-65-6Recommanded Product: 3-Butyl-1-methyl-1H-imidazol-3-ium tetrafluoroborate)

3-Butyl-1-methyl-1H-imidazol-3-ium tetrafluoroborate(cas: 174501-65-6) is a member of lonic liquids. Actually, lonic liquids as innovative fluids have received wide attention only during the past two decades. The number of SCI papers published on lonic liquids has exponentially increased from a few in 1996 to >5000 in 2016, exceeding the annual growth rates of other popular scientific areas. Recommanded Product: 3-Butyl-1-methyl-1H-imidazol-3-ium tetrafluoroborate

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

《Effects of Atractylodes Oil on Inflammatory Response and Serum Metabolites in Adjuvant Arthritis Rats》 was published in Biomedicine & Pharmacotherapy in 2020. These research results belong to Qu, Linghang; Xu, Yiyi; Cao, Guosheng; Xu, Kang; Tu, Jiyuan; Lin, Xiong; Wang, Guangzhong; Li, Shuiqing; Liu, Yanju. Name: 1H-Imidazol-2-amine The article mentions the following:

Atractylodes Rhizoma is one of two principal components in Ermiaosan, a well-known traditional Chinese medicine for the treatment of rheumatoid arthritis (RA). Atractylodes oil (AO) represents a potential alternative treatment for RA. The purpose of this study was to investigate the effect of AO in rats with Adjuvant Arthritis (AA) by exploration of changes in serum metabolites using gas chromatog.-mass spectrometry (GC-MS). Foot thickness and arthritis score, ankle joint pathol. structure, the concentrations of TNF-α, IL-1β, IL-6, IL-17 and the expression of MMPs in ankle joint tissue were measured as indicators of efficacy of treatment using AO. In addition, multivariate statistical anal. was used to identify differential production of metabolites and biomarkers, and to analyze metabolic pathways. The results demonstrate that administration of AO resulted in a good therapeutic effect in the AA rat model, with significantly improved joint swelling, reduced joint score, and inhibition of inflammation, synovial pannus hyperplasia, and bone and cartilage destruction. Furthermore, AO was found to exert its effect against rheumatoid arthritis principally by differentially affecting 11 metabolites and six metabolic pathways, predominantly related to abnormal amino acid metabolism, in addition to energy-related metabolic pathways. This study evaluated the capability of AO to effectively treat AA rats, providing a novel strategy for the treatment of RA.1H-Imidazol-2-amine(cas: 7720-39-0Name: 1H-Imidazol-2-amine) was used in this study.

1H-Imidazol-2-amine(cas: 7720-39-0) belongs to anime. Large quantities of aliphatic amines are made synthetically. The most widely used industrial method is the reaction of alcohols with ammonia at a high temperature, catalyzed by metals or metal oxide catalysts (e.g., nickel or copper). Mixtures of primary, secondary, and tertiary amines are thereby produced.Name: 1H-Imidazol-2-amine

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

《Synthetic enzyme-based nanoparticles act as smart catalyst for glucose responsive release of insulin》 was written by Jana, Baishali A.; Shinde, Ujwala; Wadhwani, Ashish. Product Details of 7720-39-0 And the article was included in Journal of Biotechnology in 2020. The article conveys some information:

This study aimed to assess faster responsiveness of insulin release from this enzyme based nanoparticles which is self-regulated insulin delivery system constructed by loading with insulin, enzyme glucose oxidase into hyaluronic acid and 2-nitroimidazole forming enzyme-based nanoparticles which works in accordance to the blood glucose level. Enzyme-based nanoparticles were prepared by ionic gelation method. Insulin content in nanoparticles kept for stability study was estimated by human insulin enzyme based immunosorbent assay. In in-vitro studies; different concentrations of glucose were taken and the release study of insulin was recorded. This enzyme-based nanoparticles were having average diameter of around 193 nm and stability studies showed that nanoparticles were stable up to 30 days at 4°C. In-vitro studies showed the release of insulin from nanoparticle conjugates which was effectively correlated with the external glucose concentration created where different concentrations of glucose taken thus facilitating the stabilization of blood glucose levels in the hyperglycemia state which was achieved within 10 min. wherein drug release rate remarkably increased in hyperglycemia state and no specific changes or small amount of release was observed in normoglycemia state (100 mg/dL). Preliminary study of this enzyme-based nanoparticles formulation showed excellent rapid responsiveness towards hyperglycemia which might act as potential biomimetic system in triggering release of insulin in sustained manner. The experimental process involved the reaction of 1H-Imidazol-2-amine(cas: 7720-39-0Product Details of 7720-39-0)

1H-Imidazol-2-amine(cas: 7720-39-0) belongs to anime. Aniline, ethanolamines, and several other amines are major industrial commodities used in making rubber, dyes, pharmaceuticals, and synthetic resins and fibres and for a host of other applications. Most of the numerous methods for the preparation of amines may be broadly divided into two groups: (1) chemical reduction (replacement of oxygen with hydrogen atoms in the molecule) of members of several other classes of organic nitrogen compounds and (2) reactions of ammonia or amines with organic compounds.Product Details of 7720-39-0

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

《Nanosilk increases the strength of diabetic skin and delivers CNP-miR146a to improve wound healing》 was written by Niemiec, Stephen M.; Louiselle, Amanda E.; Hilton, Sarah A.; Dewberry, Lindel C.; Zhang, Liping; Azeltine, Mark; Xu, Junwang; Singh, Sushant; Sakthivel, Tamil S.; Seal, Sudipta; Liechty, Kenneth W.; Zgheib, Carlos. Electric Literature of C7H6N4O And the article was included in Frontiers in Immunology in 2020. The article conveys some information:

Diabetes mellitus is a metabolic disorder associated with properties and an increased risk of chronic wounds due to sustained pro-inflammatory response. We have previously of radical scavenging cerium oxide nanoparticles (CNP) conjugated to the anti-inflammatory microRNA (miR)-146a, termed CNP-miR146a, improves diabetic wound healing by synergistically lowering oxidative stress and inflammation, and we sought to evaluate this treatment in a topical application. Silk fibroin is a biocompatible polymer that can be fabricated into nanostructures, termed nanosilk. Nanosilk is characterized by a high strength-to-d. ratio and an ability to exhibit strain hardening. We therefore hypothesized that nanosilk would strengthen the biomech. properties of diabetic skin and that nanosilk solution could effectively deliver CNP-miR146a to improve diabetic wound healing. The ability of nanosilk to deliver CNP-miR146a to murine diabetic wounds and improve healing was assessed by the rate of wound closure and inflammatory gene expression, as well as histol. anal. The effect of nanosilk on the properties of human diabetic skin was evaluated by testing the biomech. properties following topical application of a 7% nanosilk solution Diabetic murine wounds treated with topical nanosilk and CNP-miR146a healed by day 14.5 compared to day 16.8 in controls (p = 0.0321). Wounds treated with CNP-miR146a had higher collagen levels than controls (p = 0.0126) with higher pro-fibrotic gene expression of TGFβ-1 (p = 0.0092), Col3α1 (p = 0.0369), and Col1α2 (p = 0.0454). Treatment with CNP-miR146a lowered pro-inflammatory gene expression of lL-6 (p = 0.0488) and lL-8 (p = 0.0009). Treatment of human diabetic skin with 7% nanosilk solution resulted in significant improvement in maximum load and modulus (p < 0.05). Nanosilk solution is able to strengthen the biomech. properties of diabetic skin and can successfully deliver CNP-miR146a to improve diabetic wound healing through inhibition of pro-infl ammatory gene signaling and promotion of pro-fi brotic processes. In the experimental materials used by the author, we found Di(1H-imidazol-1-yl)methanone(cas: 530-62-1Electric Literature of C7H6N4O)

Di(1H-imidazol-1-yl)methanone(cas: 530-62-1) is a coupling agent in the synthesis of dipolar polyamides for nonlinear optical applications and polypeptides. It also used to make β-keto sulfones and sulfoxides, lead sequestering agents, and β-enamino acid derivatives.Electric Literature of C7H6N4O

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Zaoui, Tayeb; Debdab, Mansour; Haddad, Boumediene; Belarbi, El Habib; Chaker, Yassine; Rahmouni, Mustapha; Bresson, Serge; Baeten, Vincent published an article in 2021. The article was titled 《Synthesis, vibrational and thermal properties of new functionalized 1-(2-hydroxyethyl)-3-methylimidazolium dihydrogenophosphate ionic liquid》, and you may find the article in Journal of Molecular Structure.COA of Formula: C4H6N2 The information in the text is summarized as follows:

Very recently, the hydroxyl-functionalized ionic liquids have gained immense interest and were developed for a number of interesting applications. In this work and for the first time new hydroxyl-functionalized namely; 1-(hydroxyethyl)-3-methylimidazolium dihydrogenophosphate ionic liquid [EtOHMIM+][H2PO4-] was synthesized. The synthesis is based on an alkylation reaction of 1-methylimidazole followed by anion exchange. The obtained IL is characterized by 1H-NMR, 13C-NMR spectroscopy. Their exptl. vibrational spectroscopy have been investigated using IR and Raman spectroscopy, based on the IR (IR) and Raman spectroscopies results, complete vibrational assignments have been performed. Besides, thermal properties of this hydroxyl-functionalized IL were investigated by using following techniques, (i) thermogravimetric anal. (TGA) and derivative thermogravimetry (DTG) in the temperature range from 20 to 600°, (ii) differential scanning calorimetry (DSC) from-100° to 200°. The thermogravimetry anal. was coupled with mass spectrometry in order to assess the influence of anion on the measured property. In addition to this study using 1-Methyl-1H-imidazole, there are many other studies that have used 1-Methyl-1H-imidazole(cas: 616-47-7COA of Formula: C4H6N2) was used in this study.

1-Methyl-1H-imidazole(cas: 616-47-7) is actively involved in removing acid during the production of diethoxyphenylphosphine. It is used as an intermediate in organic synthesis.COA of Formula: C4H6N2

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Related Products of 934-32-7In 2020 ,《Synthesis, spectral, DFT calculation, sensor, antimicrobial and DNA binding studies of Co(II), Cu(II) and Zn(II) metal complexes with 2-amino benzimidazole Schiff base》 appeared in Journal of Molecular Structure. The author of the article were Kalarani, R.; Sankarganesh, M.; Kumar, G. G. Vinoth; Kalanithi, M.. The article conveys some information:

Synthesis of Co(II), Cu(II) and Zn(II) complexes of bidentate Schiff base ligand (L) 2-(1H-Benzo [d]imidazole-4-ylimmino) Me phenol is presented here. The Schiff base and its metal (II) complexes were characterized by micro anal. and spectral techniques such as AAS, UV-visible, FTIR, NMR, molar conductance and magnetic moment measurements. Molar conductance reveals the non electrolytic nature of the complexes. From the anal. and spectral anal., octahedral geometry is proposed to the synthesized metal (II) complexes. DFT calculations were done for Schiff base and metal (II) complexes to confirm the geometry of the complexes. The sensor activity of Schiff base towards calcium and magnesium ions was studied by absorption spectroscopy. Electrochem. nature of the copper(II) complex was studied by cyclic voltammetry technique and indicates the reversible nature of Cu(II)/Cu(I) couple. The antimicrobial activity of the Schiff base and its metal (II) complexes showed good potency against various microorganism such as Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa and Candida albicans. DNA binding properties of the metal complexes were studied using UV-visible absorption spectroscopy and found that the Cu(II) complex has more binding ability than L, Co(II) and Zn(II) complexes. After reading the article, we found that the author used 1H-Benzo[d]imidazol-2-amine(cas: 934-32-7Related Products of 934-32-7)

1H-Benzo[d]imidazol-2-amine(cas: 934-32-7) can be used in the hydrolysis of a choline carbonate. It was also used in the synthesis of imidazo[1,2-a]benzimidazoles.Related Products of 934-32-7

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem