Month: October 2022

In 2019,Letters in Organic Chemistry included an article by Nematpour, Manijeh; Abedi, Elham; Abedi, Elahe. HPLC of Formula: 934-32-7. The article was titled 《A Novel One-pot Protocol for the Cu-Catalyzed Synthesis of Nine 2-Aminobenzimidazole Derivatives from o-Phenylenediamine and Trichloroacetonitrile》. The information in the text is summarized as follows:

The synthesis of a variety of 2-aminobenzimidazoles I (R = H, Me, OMe, Cl, Br; R1 = H, Me, Cl; X = Y = CH, N) via one-pot reaction of o-phenylenediamine and trichloroacetonitrile catalyzed by copper (II) acetate in THF at room temperature, with good yields is described. Use of simple and readily available starting materials, good to high yields, free ligand, and ease of purification procedure are important features of this protocol. After reading the article, we found that the author used 1H-Benzo[d]imidazol-2-amine(cas: 934-32-7HPLC of Formula: 934-32-7)

1H-Benzo[d]imidazol-2-amine(cas: 934-32-7) can be used in the hydrolysis of a choline carbonate. It was also used in the synthesis of imidazo[1,2-a]benzimidazoles.HPLC of Formula: 934-32-7

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

In 2019,Organic Electronics included an article by Shanmugasundaram, Kanagaraj; John, Jino C.; Chitumalla, Srimai; Jang, Joonkyung; Choe, Youngson. Product Details of 616-47-7. The article was titled 《Carbazole based ionic small molecule emitter for non-doped light-emitting electrochemical cells》. The information in the text is summarized as follows:

Great efforts have been made to develop blue emitting organic small mols. for light-emitting electrochem. cells. Herein, blue emitting CPC (CarPhenCar) was synthesized and its emissive properties were studied. CPC exhibits blue fluorescence in toluene solution as well as in solid thin-films. CPC exhibits good thermal and electrochem. stabilities. Application of CPC mol. in solution processed light-emitting electrochem. cells resulted blue emission centered at 485 nm with brightness of 454 cd/m2, current efficiencies of 1.33 cd/A and external quantum efficiencies of 1.76%. These results adequately demonstrate the practicability of tuning the emission color of phenothiazine derivative into blue region. In the experimental materials used by the author, we found 1-Methyl-1H-imidazole(cas: 616-47-7Product Details of 616-47-7)

1-Methyl-1H-imidazole(cas: 616-47-7) is actively involved in removing acid during the production of diethoxyphenylphosphine. It is used as an intermediate in organic synthesis.Product Details of 616-47-7

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

In 2019,Journal of Applied Polymer Science included an article by Huo, Pengfei; Xun, Zhiyu; Ni, Shoupeng; Liu, Yang; Wang, Guibin; Gu, Jiyou. COA of Formula: C4H6N2. The article was titled 《Crosslinked quaternized poly(arylene ether sulfone) copolymer membrane applied in an electric double-layer capacitor for high energy density》. The information in the text is summarized as follows:

The low energy d. of supercapacitors, especially supercapacitors based on aqueous electrolytes, is the main factor limiting their application, and the energy d. is closely related to the operating potential window of the supercapacitor. The polymer electrolyte is the main contributor to the safe operation and good ion conductivity of the supercapacitor. In this study, a crosslinked quaternized poly(arylene ether sulfone) (PAES) membrane was prepared via crosslinking during membrane formation with a thermal-only treatment and applied in an elec. double-layer capacitor (EDLC). The pre-prepared PAES membrane formed a polymer electrolyte with 1 mol/L Li2SO4 and was then fabricated into an EDLC single cell. The properties of both the membrane and ELDC were investigated. The preferred cPAES-N-0.2 polymer electrolyte showed an ionic conductivity of 1.18 mS/cm. The optimized EDLC exhibited a single-electrode gravimetric capacitance of 104.92 F/g at a c.d. of 1.0 A/g and a high operating potential window (1.5 V); it, thereby, achieved a high energy d. of 8.20 W h/kg. The EDLC also exhibited excellent cycling properties over 3000 charge-discharge cycles. The crosslinked structures promoted the tensile strength and thermal stability of the PAES membranes; this was accompanied by a slight decrease in the ionic conductivity In the part of experimental materials, we found many familiar compounds, such as 1-Methyl-1H-imidazole(cas: 616-47-7COA of Formula: C4H6N2)

1-Methyl-1H-imidazole(cas: 616-47-7) is actively involved in removing acid during the production of diethoxyphenylphosphine. It is used as an intermediate in organic synthesis.COA of Formula: C4H6N2

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

The author of 《Insights on [BMIM][BF4] and [BMIM][PF6] ionic liquids and their binary mixtures with acetone and acetonitrile》 were Trenzado, J. L.; Gutierrez, A.; Alcalde, R.; Atilhan, M.; Aparicio, S.. And the article was published in Journal of Molecular Liquids in 2019. Recommanded Product: 3-Butyl-1-methyl-1H-imidazol-3-ium tetrafluoroborate The author mentioned the following in the article:

The properties of ionic liquid plus acetone or acetonitrile mixtures were studied from the macro and microscopic levels by the measurement of relevant thermophys. properties and through mol. modeling studies. The liquid mixtures were considered in the whole composition range and analyzed in terms of possible hydrogen bonding between the ions and ions with the mol. solvents. The reported results show how the large non-ideality of these systems stands on the high affinity of acetone and acetonitrile for the imidazolium hydrogen bond donor sites, which allow competition with the corresponding anions for these sites specially but not limited to mol. solvent rich mixtures The reported results allow to quantify the relevance of hydrogen bonding for the properties of ionic liquid – mol. solvent mixtures, which can be fine-tuned through the amounts of cosolvent present in the mixture as a mechanism to control mixed fluids organization. In addition to this study using 3-Butyl-1-methyl-1H-imidazol-3-ium tetrafluoroborate, there are many other studies that have used 3-Butyl-1-methyl-1H-imidazol-3-ium tetrafluoroborate(cas: 174501-65-6Recommanded Product: 3-Butyl-1-methyl-1H-imidazol-3-ium tetrafluoroborate) was used in this study.

3-Butyl-1-methyl-1H-imidazol-3-ium tetrafluoroborate(cas: 174501-65-6) is a member of lonic liquids. Actually, lonic liquids as innovative fluids have received wide attention only during the past two decades. The number of SCI papers published on lonic liquids has exponentially increased from a few in 1996 to >5000 in 2016, exceeding the annual growth rates of other popular scientific areas. Recommanded Product: 3-Butyl-1-methyl-1H-imidazol-3-ium tetrafluoroborate

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

《Some studies in sulfadiazine incorporating pyridine, pyrimidine, oxadiazole, and azo moieties endowed with pharmaceutical potency》 was published in Acta Chimica Slovenica in 2020. These research results belong to El-Hadidya, Sherihan A.; Abu-Melhab, Sraa. Computed Properties of C3H5N3 The article mentions the following:

A set of substituted sulfadiazine compounds was prepared as cytotoxic and antitumor agents by using 4-amino-N-(pyrimidin-2-yl)benzenesulfonamide (1) as the starting material. Compound 1 was reacted with different reagents to give the corresponding sulfadiazines 2-18 and hydrozaones 19a-h which were evaluated for their in vitro cytotoxicity vs. four cancer cell lines. Compounds 3, 5, 19d and 19h were active against the tested cancer cells. The experimental process involved the reaction of 1H-Imidazol-2-amine(cas: 7720-39-0Computed Properties of C3H5N3)

1H-Imidazol-2-amine(cas: 7720-39-0) belongs to anime. Milder oxidation, using reagents such as NaOCl, can remove four hydrogen atoms from primary amines of the type RCH2NH2 to form nitriles (R―C≡N), and oxidation with reagents such as MnO2 can remove two hydrogen atoms from secondary amines (R2CH―NHR′) to form imines (R2C=NR′). Tertiary amines can be oxidized to enamines (R2C=CHNR2) by a variety of reagents.Computed Properties of C3H5N3

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

《Grafted nanocellulose and alkaline nanoparticles for the strengthening and deacidification of cellulosic artworks》 was published in Journal of Colloid and Interface Science in 2020. These research results belong to Xu, Q.; Poggi, G.; Resta, C.; Baglioni, M.; Baglioni, P.. Category: imidazoles-derivatives The article mentions the following:

Strongly degraded cellulosic artworks usually need deacidification and consolidation. Alk. nanoparticles are known to be effective in neutralizing the acidity, while cellulose nanocrystals have the potential to be used as compatible and effective strengthening agents. We have grafted cellulose nanocrystals with oleic acid using a 1’1-carbonyldiimidazole-mediated procedure, to increase their dispersibility in organic solvents, and synthesized Ca(OH)2 or CaCO3 nanoparticles via a solvothermal process. Grafted nanocellulose and alk. nanoparticles were used to prepare ethanol-based “”hybrids””. Prior to the application, the physico-chem. properties of nanocellulose dispersions and “”hybrids”” were studied by rheol. and small-angle X-ray scattering. Cellulose nanocrystals were effectively grafted and stably dispersed in ethanol. It was shown that the use of ethanol as a dispersing medium, and the addition of alk. nanoparticles act in a synergistic way, increasing the interactions between grafted cellulose nanocrystals, leading to the formation of clusters. These dispersions are thixotropic, a behavior particularly appealing to conservation purposes, since they can be applied in the liquid state, or, when a more confined application is required, they can be applied in a gel-like state. As a result of the application, an improvement in the mech. properties of paper and an increase of pH were obtained. In the experimental materials used by the author, we found Di(1H-imidazol-1-yl)methanone(cas: 530-62-1Category: imidazoles-derivatives)

Di(1H-imidazol-1-yl)methanone(cas: 530-62-1) is a peptide coupling reagent,it is used in the synthesis of peptides. Reacts readily with carboxylic acids to form acyl imidazoles; subsequent reaction with amines to form amides goes smoothly.Category: imidazoles-derivatives

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

《Controlling the nanoscale friction by layered ionic liquid films》 was written by An, Rong; Qiu, Xiuhua; Shah, Faiz Ullah; Riehemann, Kristina; Fuchs, Harald. COA of Formula: C8H15BF4N2 And the article was included in Physical Chemistry Chemical Physics in 2020. The article conveys some information:

The nanofriction coefficient of ionic liquids (ILs), 1-butyl-3-methylimidazolium tetrafluoroborate ([BMIM][BF4]) and 1-butyl-3-methylimidazolium hexafluorophosphate ([BMIM][PF6]), on the surfaces of mica and graphite was investigated using at. force microscopy (AFM). A pronounced layered spatial distribution was found in the IL film formed on the solid substrates and can be divided into 3 well distinguishable regions exhibiting different phys. properties with increasing distance from the substrate. We found that the friction coefficient (μ) increases monotonically as the layering thickness decreases, no matter what the thickness of the bulk IL is. This suggests that the layering assembled IL at solid surfaces is more important than the bulk phase in determining the magnitude of the nanoscale friction. The increase in the friction coefficient as the layering thickness decreases is most likely attributed to the assembled ordered IL layers closer to the substrate surfaces having a greater activation barrier for unlocking the surfaces to allow shear. In the experimental materials used by the author, we found 3-Butyl-1-methyl-1H-imidazol-3-ium tetrafluoroborate(cas: 174501-65-6COA of Formula: C8H15BF4N2)

3-Butyl-1-methyl-1H-imidazol-3-ium tetrafluoroborate(cas: 174501-65-6) is a member of lonic liquids. A multidisciplinary study on lonic liquids is emerging, including chemistry, materials science, chemical engineering, and environmental science. More specifically, some important fundamental viewpoints are now different from the original concepts, as insights into the nature of lonic liquids become deeper. For example, the physicochemical properties of lonic liquids are now recognized as ranging broadly from the oft quoted “nonvolatile, non-flammable, and air and water stable” to those that are distinctly volatile, flammable, and unstable. COA of Formula: C8H15BF4N2

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

《Metal-Organic Frameworks Conjugated Lipase with Enhanced Bio-catalytic Activity and Stability》 was written by Zou, Bin; Zhang, Liming; Xia, Jiaojiao; Wang, Pengyun; Yan, Yan; Wang, Xinyi; Adesanya, Idowu Onyinye. Related Products of 530-62-1 And the article was included in Applied Biochemistry and Biotechnology in 2020. The article conveys some information:

Covalent immobilization of lipase onto a solid carrier is an effective way to enhance stability. Immobilization inhibits the activity of lipase due to decreased flexibility of enzyme structure via the covalent bond. In this study, monomer of the metal-organic frameworks (MOFs) material ZIF-8 (2-Me imidazole-4-carboxylic acid) was innovatively used as a chem. modifier of Candida nrugosa lipase (CRL). The CD spectra results show that the CRL mol. was altered by chem. modification and thus its catalytic activity was 1.3 times higher than that of the free CRL. The modified CRL mol. was further immobilized in the “”skeleton”” of ZIF-8 through the monomer while in situ forming the cell skeleton of the MOFs, which prevent the active center from being destroyed. The results show that conjugation of chem. modification and immobilized enzymes ensure that there was no obvious reduction in the activity of CRL after immobilization and the stability of CRL was improved. Especially, the organic solvent stability of the modified immobilization CRL in isopropanol was significantly improved and retained more than 148% of its activity.Di(1H-imidazol-1-yl)methanone(cas: 530-62-1Related Products of 530-62-1) was used in this study.

Di(1H-imidazol-1-yl)methanone(cas: 530-62-1) is a coupling agent in the synthesis of dipolar polyamides for nonlinear optical applications and polypeptides. It also used to make β-keto sulfones and sulfoxides, lead sequestering agents, and β-enamino acid derivatives.Related Products of 530-62-1

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Atkinson, Ariel J.; Armstrong, Mikayla D.; Eskew, John T.; Coronell, Orlando published their research in Journal of Membrane Science in 2021. The article was titled 《Aminoimidazole reduces fouling and improves membrane performance》.Reference of 1H-Imidazol-2-amine The article contains the following contents:

Biofouling is difficult to control and hinders the performance of membranes in all applications but is of particular concern when natural waters are purified. Fouling, via multiple mechanisms (organic-only, biofouling-only, cell-deposition-only, and organic + biofouling), of a com. available membrane (control) and a corresponding membrane coated with an anti-biofouling 2-aminoimidazole (2-AI membrane) was monitored and characterized during the purification of a natural water. Results show that the amount of bacterial cell deposition and organic fouling was not significantly different between control and 2-AI membranes; however, biofilm formation, concurrent or not with other fouling mechanisms, was significantly inhibited (95-98%, p < 0.001) by the 2-AI membrane. The limited biofilm that formed on the 2-AI membrane was weaker (as indicated by the polysaccharide to protein ratio) and thus presumably easier to remove. The conductivity rejection by the 2-AI and control membranes was not significantly different throughout the 75-h experiments, but the rejection of dissolved organic carbon by biofouled (biofouling-only, cell-deposition-only, and organic + biofouling) 2-AI membranes was statistically higher (10-12%, p = 0.003-0.07). When biofouled, the water permeance of the 2-AI membranes decreased significantly less (p < 0.05) over 75 h than that of the control membranes, whether or not other addnl. types of fouling occurred concurrently. Despite the initially lower water permeances of 2-AI membranes (11% lower on average than controls), the 2-AI membranes outperformed the controls (10-11% higher average water permeance) after biofilm formation occurred. Overall, 2-AI membranes fouled less than controls without detriment to water productivity and solute rejection. The experimental process involved the reaction of 1H-Imidazol-2-amine(cas: 7720-39-0Reference of 1H-Imidazol-2-amine)

1H-Imidazol-2-amine(cas: 7720-39-0) belongs to anime. Aniline, ethanolamines, and several other amines are major industrial commodities used in making rubber, dyes, pharmaceuticals, and synthetic resins and fibres and for a host of other applications. Most of the numerous methods for the preparation of amines may be broadly divided into two groups: (1) chemical reduction (replacement of oxygen with hydrogen atoms in the molecule) of members of several other classes of organic nitrogen compounds and (2) reactions of ammonia or amines with organic compounds.Reference of 1H-Imidazol-2-amine

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Kumar, D. Sharath; Pallavi, H. S.; Pullela, Phani Kumar published their research in Asian Journal of Chemistry in 2021. The article was titled 《Detection of non-nitro compounds by amplified fluorescence polymer (AFP): an opportunity for breath-based disease diagnosis》.Synthetic Route of C21H25ClN2 The article contains the following contents:

Amplified fluorescence polymers (AFP) are a set of unique polymers known for their ability to detect trace nitro explosives. The prior knowledge in the AFP field indicates that the functional group variation on the polymer backbone is responsible for the selectivity of an analyte. The mechanism of analyte detection is believed that only compounds with nitro functional groups are detected by AFP. Usually, AFP functional groups varied to detect nitro compounds and the non-nitro compound detection and the mechanism of the AFP were not completely understood. In this work, the AFP polymer was kept constant and studied with 136 analytes with different functional groups for analyzing few non-nitro compounds Among the 136 compounds analyzed, about fourteen have been detected by AFP. It was observed that most of the fourteen compounds were non-nitro compounds The mechanism proposed originally for nitro compounds and associated hypothesises the existence of a parking space on the polymer backbone. Present study suggested that the possibility of only nitro compounds interacting with AFP due to the three-dimensional shape of the analyte as the detrimental factor. The discovery of non-nitro compound detection by AFP opens up the use of AFP for gas-phase disease volatile organic compound detection. Future studies of functional group variation on the AFP backbone in relation to the analyte detection could provide insights into the relation of analyte detection by AFP and the parameters to optimize for obtaining the selectivity and specificity. In the experiment, the researchers used 1,3-Dimesityl-1H-imidazol-3-ium chloride(cas: 141556-45-8Synthetic Route of C21H25ClN2)

1,3-Dimesityl-1H-imidazol-3-ium chloride(cas: 141556-45-8) is a ligand for arylation of aldehydes and for carbene catalyzed intermolecular arylation of C-H bonds. It is used as a phosphine-free ligand in various metal-catalyzed coupling reactions, often with advantageous results in difficult cases.Synthetic Route of C21H25ClN2

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem