On December 31, 2021, Chaturvedi, Anurag; Cruz Corella, Joaquim; Robbins, Chanz; Loha, Anita; Menin, Laure; Gasilova, Natalia; Masclaux, Frederic G.; Lee, Soon-Jae; Sanders, Ian R. published an article.Formula: C6H7N5 The title of the article was The methylome of the model arbuscular mycorrhizal fungus, Rhizophagus irregularis, shares characteristics with early diverging fungi and Dikarya. And the article contained the following:
Early-diverging fungi (EDF) are distinct from Dikarya and other eukaryotes, exhibiting high N6-methyldeoxyadenine (6mA) contents, rather than 5-methylcytosine (5mC). As plants transitioned to land the EDF sub-phylum, arbuscular mycorrhizal fungi (AMF; Glomeromycotina) evolved a symbiotic lifestyle with 80% of plant species worldwide. Here we show that these fungi exhibit 5mC and 6mA methylation characteristics that jointly set them apart from other fungi. The model AMF, R. irregularis, evolved very high levels of 5mC and greatly reduced levels of 6mA. However, unlike the Dikarya, 6mA in AMF occurs at sym. ApT motifs in genes and is associated with their transcription. 6MA is heterogeneously distributed among nuclei in these coenocytic fungi suggesting functional differences among nuclei. While far fewer genes are regulated by 6mA in the AMF genome than in EDF, most strikingly, 6mA methylation has been specifically retained in genes implicated in components of phosphate regulation; the quintessential hallmark defining this globally important symbiosis. The experimental process involved the reaction of N-Methyl-7H-purin-6-amine(cas: 443-72-1).Formula: C6H7N5
The Article related to rhizophagus irregularis arbuscular mycorrhizal fungus characteristic methyldeoxyadenine methylcytosine, Microbial, Algal, and Fungal Biochemistry: Classical Genetics and other aspects.Formula: C6H7N5
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem