On June 30, 1978, Marzilli, Luigi G.; Hanson, Brian E.; Kapili, Leilani; Rose, Seth D.; Beer, Michael published an article.Computed Properties of 55662-66-3 The title of the article was Osmium-labeled polynucleotides: reaction of osmium tetraoxide, with poly-1,N6-ethenoadenylic acid. And the article contained the following:
OsO4, in the presence of ligands such as pyridine and bipyridine, added across the etheno bridge of 1,N6-etheno-9-methyladenine and poly(1,N6-ethenoadenylic acid). The Os:P ratio in the labeled polynucleotide was ≃1 when bipyridine was used as the stabilizing ligand. A similar study with poly(C), which was partially modified with chloroacetaldehyde so that some bases were converted to 3,N4-ethenocytosine, gave an Os:P ratio of ≃1.3. Calf thymus DNA, in which adenine and cytosine bases were modified by chloroacetaldehyde, gave an Os:P ratio of ≃1 after 24 h. Thus, 3,N4-ethenocytosine may add 2 Os labels. The experimental process involved the reaction of Imidazo[1,2-c]pyrimidin-5(6H)-one(cas: 55662-66-3).Computed Properties of 55662-66-3
The Article related to polyethenoadenylate addition reaction osmium, ethenoadenylate polymer reaction osmium, ethenycytosine reaction osmium, General Biochemistry: Nucleic Acids and Their Constituents and other aspects.Computed Properties of 55662-66-3
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem