On September 30, 2007, El Alaoui, Abdessamad; Schmidt, Frederic; Amessou, Mohamed; Sarr, Marianne; Decaudin, Didier; Florent, Jean-Claude; Johannes, Ludger published an article.Recommanded Product: 901770-40-9 The title of the article was Shiga toxin-mediated retrograde delivery of a topoisomerase I inhibitor prodrug. And the article contained the following:
A retrograde strategy: An innovative cancer-cell delivery concept exploits the naturally evolved characteristics of the Shiga toxin B-subunit (STxB) for the intracellular activation of a newly synthesized prodrug at the level of the biosynthetic/secretory pathway. Retrograde prodrug targeting allows its slow release, which should sustain the presence of the active principle in dividing tumor cells. The experimental process involved the reaction of N-(4-Hydroxyphenyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide(cas: 901770-40-9).Recommanded Product: 901770-40-9
The Article related to shiga toxin retrograde delivery topoisomerase i inhibitor prodrug, Pharmaceuticals: Pharmaceutics and other aspects.Recommanded Product: 901770-40-9
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem