Ryder, Alison S. H. et al. published their research in Angewandte Chemie, International Edition in 2020 |CAS: 5036-48-6

The Article related to photocatalyst alpha tertiary amine preparation alkylation, c鈭抙 activation, amines, photocatalysis, radicals, spiro compounds, General Organic Chemistry: Synthetic Methods and other aspects.Related Products of 5036-48-6

Ryder, Alison S. H.; Cunningham, William B.; Ballantyne, George; Mules, Tom; Kinsella, Anna G.; Turner-Dore, Jacob; Alder, Catherine M.; Edwards, Lee J.; McKay, Blandine S. J.; Grayson, Matthew N.; Cresswell, Alexander J. published an article in 2020, the title of the article was Photocatalytic ä¼?Tertiary Amine Synthesis via C-H Alkylation of Unmasked Primary Amines.Related Products of 5036-48-6 And the article contains the following content:

A practical, catalytic entry to ä¼?ä¼?ä¼?trisubstituted (ä¼?tertiary) primary amines by C-H functionalization has long been recognized as a critical gap in the synthetic toolbox. The authors report a simple and scalable solution to this problem that does not require any in situ protection of the amino group and proceeds with 100% atom-economy. The authors’ strategy, which uses an organic photocatalyst in combination with azide ion as a hydrogen atom transfer (HAT) catalyst, provides a direct synthesis of ä¼?tertiary amines, or their corresponding çº?lactams. The authors anticipate that this methodol. will inspire new retrosynthetic disconnections for substituted amine derivatives in organic synthesis, and particularly for challenging ä¼?tertiary primary amines. The experimental process involved the reaction of N-(3-Aminopropyl)-imidazole(cas: 5036-48-6).Related Products of 5036-48-6

The Article related to photocatalyst alpha tertiary amine preparation alkylation, c鈭抙 activation, amines, photocatalysis, radicals, spiro compounds, General Organic Chemistry: Synthetic Methods and other aspects.Related Products of 5036-48-6

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem