Zink, Laura’s team published research in Tetrahedron Letters in 2011 | CAS: 18874-52-7

Tetrahedron Letters published new progress about Radical nucleophilic substitution reaction. 18874-52-7 belongs to class imidazoles-derivatives, name is 5-Bromo-2-methyl-4-nitroimidazole, and the molecular formula is C4H4BrN3O2, Product Details of C4H4BrN3O2.

Zink, Laura published the artcileLong distance-SRN1 in nitroimidazole series favored by temperature, Product Details of C4H4BrN3O2, the main research area is long distance unimol radical nucleophilic substitution reaction nitroimidazole; imidazole nitro long distance unimol radical nucleophilic substitution.

New reductive alkylating agents in 4- and 5-nitroimidazole series produce exclusively O-alkylation with nitronate anions under classical SRN1 conditions at room temperature Electron-transfer C-alkylation is observed under microwave irradiation or under conventional heating. Furthermore, X-ray spectroscopy shows that the dihedral angles between the Ph and imidazole rings for the two series are different, which could greatly influence reactivity in 4- and 5-nitroimidazole series.

Tetrahedron Letters published new progress about Radical nucleophilic substitution reaction. 18874-52-7 belongs to class imidazoles-derivatives, name is 5-Bromo-2-methyl-4-nitroimidazole, and the molecular formula is C4H4BrN3O2, Product Details of C4H4BrN3O2.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem