Casella, Luigi published the artcileHemocyanin and tyrosinase models. Synthesis, azide binding, and electrochemistry of dinuclear copper(II) complexes with poly(benzimidazole) ligands modeling the met forms of the proteins, Quality Control of 4760-35-4, the publication is Inorganic Chemistry (1993), 32(10), 2056-67, database is CAplus.
The new poly(benzimidazole) ligands α,α’-bis[[bis(1-methyl-2-benzimidazolyl)methyl]amino]-m-xylene (L-5,5) and α,α’-bis[bis[2-(1-methyl-2-benzimidazolyl)ethyl]amino]-m-xylene (L-6,6) and their dicopper(I) and bis(aqua)-dicopper(II) complexes are reported. The ligands provide 1 tertiary amino and 2 benzimidazole N donors to each metal center; each of the 2 arms of L-5,5 binds the metal with 2 adjacent 5-membered chelate rings, while with L-6,6 these chelate rings are 6-membered. The dicopper(I) complexes react with dioxygen to produce the bis(hydroxo)dicopper(II) complexes. The bis(aqua)- and bis(hydroxo)dicopper(II) complexes can be interconverted in a single step by addition of base and acid, resp. The electrochem. behavior of the bis(aqua)dicopper(II) complex of L-6,6 shows reversible reduction to the corresponding dicopper(I) complex whereas the analogous complex of L-5,5 is irreversibly reduced. The bis(hydroxo)dicopper(II) complexes of both ligands also undergo irreversible reduction Azide adducts of the dicopper(II) complexes were isolated; the anion bridges the 2 coppers in μ-1,1 fashion in the L-5,5 derivative and in μ-1,3 fashion in the L-6,6 derivative The spectral properties of the 2 complexes are significantly different. Binding studies performed in solution for the bis(aqua)- and bis(hydroxo)dicopper(II) complexes show that up to 4 azide mol. can bind to the complexes and the affinity of azide decreases with the charge of the complex. Electrochem. shows that, upon increasing the number of bound azide groups, the successive reductions of the 2 Cu(II) centers tend to coalesce, thus indicating progressive lowering of the electronic communication between the metal centers. The relevance of the spectroscopic and binding data of these azide complexes to hemocyanin and tyrosinase is discussed.
Inorganic Chemistry published new progress about 4760-35-4. 4760-35-4 belongs to imidazoles-derivatives, auxiliary class Chloride,Benzimidazole, name is 2-(Chloromethyl)-1-methyl-1H-benzo[d]imidazole, and the molecular formula is C9H9ClN2, Quality Control of 4760-35-4.
Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem