Kassem, A. A. published the artcileProlonged release antazoline hydrochloride tablets. Part II. Using repeated granulation technique, Product Details of C17H20ClN3, the publication is Bulletin of the Faculty of Pharmacy (Cairo University) (1976), 14(1), 187-205, database is CAplus.
Repeated granulation of antazoline-HCl (I) [2508-72-7] with 5% and 10% Et cellulose [9004-57-3] and shellac solutions, followed by release-time study of the drug from its tablets, showed no increase in the release proportional to the concentration of the former binder. However, with shellac the increase in the release time was proportional to the concentration increase. In both cases, the release of I was relatively more rapid in gastric fluid than in that observed in intestinal fluid. The effects of number of granulations and surface area of the tablet on drug release were also studied. Shellac was more effective than Et cellulose in reducing the release of the drug.
Bulletin of the Faculty of Pharmacy (Cairo University) published new progress about 2508-72-7. 2508-72-7 belongs to imidazoles-derivatives, auxiliary class Inhibitor,Immunology/Inflammation,Histamine Receptor, name is N-Benzyl-N-((4,5-dihydro-1H-imidazol-2-yl)methyl)aniline hydrochloride, and the molecular formula is C17H20ClN3, Product Details of C17H20ClN3.
Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem