Nusz, Greg J. published the artcileRational Selection of Gold Nanorod Geometry for Label-Free Plasmonic Biosensors, Related Products of imidazoles-derivatives, the publication is ACS Nano (2009), 3(4), 795-806, database is CAplus and MEDLINE.
The authors present the development of an anal. model that can be used for the rational design of a biosensor based on shifts in the local surface plasmon resonance (LSPR) of individual gold nanoparticles. The model relates the peak wavelength of light scattered by an individual plasmonic nanoparticle to the number of bound analyte mols. and provides an anal. formulation that predicts relevant figures-of-merit of the sensor such as the mol. detection limit (MDL) and dynamic range as a function of nanoparticle geometry and detection system parameters. The model calculates LSPR shifts for individual mols. bound by a nanorod, so that the MDL is defined as the smallest number of bound mols. that is measurable by the system, and the dynamic range is defined as the maximum number of mols. that can be detected by a single nanorod. This model is useful because it will allow a priori design of an LSPR sensor with figures-of-merit that can be optimized for the target analyte. This model was used to design an LSPR sensor based on biotin-functionalized gold nanorods that offers the lowest MDL for this class of sensors. The model predicts a MDL of 18 streptavidin mols. for this sensor, which is in good agreement with experiments and estimates Further, the authors discuss how the model can be utilized to guide the development of future generations of LSPR biosensors.
ACS Nano published new progress about 359860-27-8. 359860-27-8 belongs to imidazoles-derivatives, auxiliary class Other Aliphatic Heterocyclic,Chiral,Amine,Amide,Ether,Inhibitor, name is N-(2-(2-(2-(2-Aminoethoxy)ethoxy)ethoxy)ethyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide, and the molecular formula is C18H34N4O5S, Related Products of imidazoles-derivatives.
Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem