Secci, Daniela published the artcileConventional and microwave-assisted synthesis of benzimidazole derivatives and their in vitro inhibition of human cyclooxygenase, Synthetic Route of 2622-67-5, the publication is Journal of Heterocyclic Chemistry (2012), 49(5), 1187-1195, database is CAplus.
1,2-Diaryl- and 2-aryl-1H-benzimidazoles were synthesized using both microwave irradiation and conventional heating methods. Usually higher yields and reaction time reduction were obtained with the former method. All compounds were assayed for their in vitro ability to inhibit human cyclooxygenases, and most of them showed an encouraging inhibitory activity and isoform selectivity in the micromolar range.
Journal of Heterocyclic Chemistry published new progress about 2622-67-5. 2622-67-5 belongs to imidazoles-derivatives, auxiliary class Benzimidazole,Benzene,Benzimidazole, name is 1,2-Diphenyl-1H-benzo[d]imidazole, and the molecular formula is C16H10O5, Synthetic Route of 2622-67-5.
Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem