Soonthonhut, Siraporn published the artcileIonic Liquid Driven Nucleophilic Substitution of Squaric Acid to Squaramides, Quality Control of 79917-90-1, the publication is Synlett (2022), 33(14), 1347-1352, database is CAplus.
The synthesis of squaramides such as I [R1 = H, C6H5; R2 = n-Bu, C6H5, 4-BrC6H4, etc.] through [bmim]Cl-mediated nucleophilic substitution of squaric acid with amine nucleophiles was reported. Owing to remarkable solvating ability of ionic liquid, reactions of squaric acid with a variety of structurally diverse amine nucleophiles were achieved. Interestingly, a catalyst-free reaction in [bmim]Cl could produce squaramides up to 99% yield. With the same efficacies, [bmim]Cl could be reused for at least three cycles. The catalyst-free, ionic liquid mediated approach expanded the reactant scope and offered a simple, efficient, and environmentally friendly synthesis of squaramides.
Synlett published new progress about 79917-90-1. 79917-90-1 belongs to imidazoles-derivatives, auxiliary class Ionic Liquid,Ionic Liquid, name is 3-Butyl-1-methyl-1H-imidazol-3-ium chloride, and the molecular formula is C3H12Cl2N2, Quality Control of 79917-90-1.
Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem