Wang, Xing published the artcileSynthesis and biological evaluation of benzimidazole phenylhydrazone derivatives as antifungal agents against phytopathogenic fungi, Related Products of imidazoles-derivatives, the publication is Molecules (2016), 21(11), 1574/1-1574/14, database is CAplus and MEDLINE.
A series of benzimidazole phenylhydrazone derivatives I (R1 = H, CH3, Cl; R2 = H, CH3; R3 = 2,4-F2, 3,5-Cl2, 2,6-Cl2, etc.) was synthesized. The structure of I (R1 = H; R2 = H; R2 = 2-F) was further confirmed by single crystal X-ray diffraction as (E)-configuration. All the compounds were screened for antifungal activity against Rhizoctonia solani and Magnaporthe oryzae employing a mycelium growth rate method. Compound I (R1 = H; R2 = H; R2 = 2,4-F2) exhibited significant inhibitory activity against R. solani and M. oryzae with the EC50 values of 1.20 and 1.85 μg/mL, resp. In vivo testing demonstrated that I (R1 = H; R2 = H; R2 = 2,4-F2) could effectively control the development of rice sheath blight (RSB) and rice blast (RB) caused by the above two phytopathogens. This work indicated that the compound I (R1 = H; R2 = H; R2 = 2,4-F2) with a benzimidazole phenylhydrazone scaffold could be considered as a leading structure for the development of novel fungicides.
Molecules published new progress about 7467-35-8. 7467-35-8 belongs to imidazoles-derivatives, auxiliary class Benzimidazole,Alcohol, name is (1-Methyl-1H-benzo[d]imidazol-2-yl)methanol, and the molecular formula is C13H10O3, Related Products of imidazoles-derivatives.
Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem