Woo, Ho Bum published the artcileSynthesis of substituted benzimidazolyl curcumin mimics and their anticancer activity, COA of Formula: C9H10N2O, the publication is Bioorganic & Medicinal Chemistry Letters (2012), 22(2), 933-936, database is CAplus and MEDLINE.
A novel curcumin mimic library possessing variously substituted benzimidazole groups was synthesized through the aldol reaction of I or II with diversely substituted benzimidazolyl-2-carbaldehydes. The MTT assay of the cancer cells MCF-7, SH-SY5Y, HEP-G2, and H460 showed that compound III with IC50 of 1.0 and 1.9 μM has a strong inhibitory effect on the growth of SH-SY5Y and Hep-G2 cells, resp., and that compound IV with IC50 of 1.9 μM has a strong inhibitory effect on the growth of MCF-7 cancer cells.
Bioorganic & Medicinal Chemistry Letters published new progress about 7467-35-8. 7467-35-8 belongs to imidazoles-derivatives, auxiliary class Benzimidazole,Alcohol, name is (1-Methyl-1H-benzo[d]imidazol-2-yl)methanol, and the molecular formula is C24H12, COA of Formula: C9H10N2O.
Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem