Synthesis of gossypol acetate with [HMIm]HSO4 ionic liquid as catalyst was written by Dong, Shihong;Wang, Dan;Zhu, Mingyuan;Dai, Bin. And the article was included in Zhongguo Youzhi in 2012.Application of 478935-29-4 The following contents are mentioned in the article:
With Bronsted acidic ionic liquid [HMIm]HSO4 as the catalyst, the synthesis of gossypol acetate was investigated. The effects of reaction conditions including temperature, reaction time, material ratio and amount of catalyst on the yield of the reaction were also investigated. The optimal reaction conditions were as follows: reaction temperature 10°C, volume ratio of gossypol to glacial acetic acid-[HMIm]HSO4 1:1.0, amount of catalyst 6%(based on the mass of glacial acetic acid) and reaction time 4 h. Under these conditions, the yield of gossypol acetate reached 93%. At the same time, the stability and acidity of ionic liquid([HMIm]HSO4) were investigated using thermogravimetric anal. and UV spectroscopy detection. The ionic liquid [HMIm]HSO4 had a stable catalytic activity even after 4 cycles. This study involved multiple reactions and reactants, such as 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4Application of 478935-29-4).
1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4) belongs to imidazole derivatives. Many natural products, especially alkaloids, contain the imidazole ring. These imidazoles share the 1,3-C3N2 ring but feature varied substituents. This ring system is present in important biological building blocks, such as histidine and the related hormone histamine.Application of 478935-29-4
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem