Synthesis of aethylparabenum catalyzed by task-specific acidic ionic liquid was written by Tan, Feng;Hu, Rong;Yang, Xue-jun;Li, Jun-yang. And the article was included in Xinan Minzu Daxue Xuebao, Ziran Kexueban in 2008.COA of Formula: C10H20N2O4S The following contents are mentioned in the article:
P-hydroxybenzoic acid and anhydrous ethanol are used to synthesize aethylparabenum with novel Bronsted activated [Hmim]HSO4 as the catalyst. The influences of the reaction period, the mole ratio between alc. and acid, and the amount of ionic fluid on the ester yield were investigated. The optimized reaction condition is confirmed, according to which the reaction period should be 2.5 h, the mole ratio between alc. and acid should be 1:1.5, and the amount of ionic fluid should be 3 mL. Under this optimized condition, the ester yield could achieve 81.5%, and the ionic fluid could be used for 5 times repeatedly without any change of its catalytic efficiency. This study involved multiple reactions and reactants, such as 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4COA of Formula: C10H20N2O4S).
1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4) belongs to imidazole derivatives. 1H-imidazole is an imidazole tautomer which has the migrating hydrogen at position 1. It is a conjugate base of an imidazolium cation. It is a conjugate acid of an imidazolide. It is a tautomer of a 4H-imidazole. Imidazole based anticancer drug find applications in cancer chemotherapy. It is used as buffer component for purification of the histidine tagged recombinant proteins in immobilized metal-affinity chromatography (IMAC).COA of Formula: C10H20N2O4S
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem