Highly selective synthesis for 4,4′-bisphenol F from phenol and formaldehyde catalyzed with [C4min][HSO4] ionic liquid was written by Wang, Danfeng;He, Zhicheng;Wu, Zhimin;Tan, Ying;Li, Yongfei;Liu, Yuejin. And the article was included in Chinese Journal of Chemical Engineering in 2016.Category: imidazoles-derivatives The following contents are mentioned in the article:
The effects of N-methylimidazole cation [Cnmin] with different alkyl chain lengths, the types of cations and anions of ionic liquids and the reaction parameters on the catalytic activity and the selectivity for 4,4′-bisphenol F were investigated. The hydrogen bonding between the hydroxyl of phenol and the C2-position hydrogen of imidazole moiety in hydrophilic imidazole-based ionic liquid has important influence on the selectivity for 4,4′-bisphenol F, and under the conditions of the molar ratio of phenol/[C4min][HSO4] 1:1, reaction temperature 65°C and the theor. molar ratio of phenol/formaldehyde 2:1, the selectivity for 4,4′-bisphenol F reached 69.1%. Compared with the high phenol/formaldehyde ratio reported in literatures, the low molar ratio of phenol/formaldehyde and the low reaction temperature could greatly reduce energy consumption, and had important significance for industrial application. This study involved multiple reactions and reactants, such as 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4Category: imidazoles-derivatives).
1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4) belongs to imidazole derivatives. Imidazole is the basic core of some natural products such as histidine, purine, histamine and DNA based structures, etc. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole based anticancer drug find applications in cancer chemotherapy. It is used as buffer component for purification of the histidine tagged recombinant proteins in immobilized metal-affinity chromatography (IMAC).Category: imidazoles-derivatives
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem