Synthesis of 1,5-benzodiazepine derivatives catalyzed by acidic ionic liquid was written by Xu, Qiu-yan;Ji, Shun-jun;Gu, Da-gong. And the article was included in Hecheng Huaxue in 2005.HPLC of Formula: 478935-29-4 The following contents are mentioned in the article:
A novel method was reported that 1,5-benzodiazepine derivatives were synthesized via the condensation of o-phenylenediamines with ketones using acidic ionic liquid and alc. as a catalyst system. Target compounds thus prepared included 2,3-Dihydro-2,2,4-trimethyl-1H-1,5-benzodiazepine, 2-ethyl-2,3-dihydro-2,3,4-trimethyl-1H-1,5-benzodiazepine, 2,3,9,10a-tetrahydrospiro[benzo[b]cyclopenta[e][1,4]diazepine-10(1H),1′-cyclopentane], etc. The ionic liquid used in this study was 1-he;yl-3-methyl-1H-imidazolium hydrogen sulfate. This catalyst system can be reused three times. This study involved multiple reactions and reactants, such as 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4HPLC of Formula: 478935-29-4).
1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4) belongs to imidazole derivatives. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole has become an important synthon in the development of new drugs. This ring system is present in important biological building blocks, such as histidine and the related hormone histamine.HPLC of Formula: 478935-29-4
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem