Cho, Woo Kyung published the artcileChemical modification of Si nanowires for bioconjugation, Safety of N-(2-(2-(2-(2-Aminoethoxy)ethoxy)ethoxy)ethyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide, the publication is Bulletin of the Korean Chemical Society (2005), 27(1), 111-114, database is CAplus.
The authors report the chem. modification of SiNWs (Si nanowires) by a combination of the formation of covalently bonded, organic monolayers on the surface of SiNWs and successive surface organic reactions. Self-assembled monolayers (SAMs) of 10-undecenyltrichlorosilane were formed on the surface of SiNWs. The terminal vinyl groups on the surface of SiNWs were oxidized to carboxylic acid groups by KMnO4, K2CO3, and NaIO3. The carboxylic acid groups were then activated with N-(3-dimethylaminopropyl)-N’-ethylcarbodiimide hydrochloride (EDC) and pentafluorophenol (PFP). The formation of the SAMs on SiNWs and the successive reactions were confirmed by polarized IR external reflectance spectroscopy (PIERS). After the PFP activation, any mols. with amine functional groups can be anchored onto the surface of SiNWs through an amide bond. The PFP-activated SiNWs were washed carefully with EtOH several times. The sample was then immersed in a solution of biotin-amine (10 mM in EtOH) for 30 min and washed carefully with EtOH several times. Attachment of the biotin to the SiNWs was verified PIERS and fluorescence confocal microscopy. By sonication, the SiNWs were then separated from the Si wafer and dispersed in EtOH. The dispersed SiNWs were spun off by using centrifugation.
Bulletin of the Korean Chemical Society published new progress about 359860-27-8. 359860-27-8 belongs to imidazoles-derivatives, auxiliary class Other Aliphatic Heterocyclic,Chiral,Amine,Amide,Ether,Inhibitor, name is N-(2-(2-(2-(2-Aminoethoxy)ethoxy)ethoxy)ethyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide, and the molecular formula is C18H34N4O5S, Safety of N-(2-(2-(2-(2-Aminoethoxy)ethoxy)ethoxy)ethyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide.
Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem