Kam, Nadine Wong Shi published the artcileNanotube molecular transporters: internalization of carbon nanotube-protein conjugates into mammalian cells, Formula: C18H34N4O5S, the publication is Journal of the American Chemical Society (2004), 126(22), 6850-6851, database is CAplus and MEDLINE.
The interactions between various functionalized carbon nanotubes and several types of human cancer cells are explored. We have prepared modified nanotubes and have shown that these can be derivatized in a way that enables attachment of small mols. and of proteins, the latter through a novel noncovalent association The functionalized carbon nanotubes enter nonadherent human cancer cells as well as adherent cell lines (CHO and 3T3) and by themselves are not toxic. While the fluoresceinated protein streptavidin (MW ≈ 60 kD) by itself does not enter cells, it readily enters cells when complexed to a nanotube-biotin transporter and exhibits dose-dependent cytotoxicity. The uptake pathway is consistent with adsorption-mediated endocytosis. The use of carbon nanotubes as mol. transporters could be exploited for various cargos. The biocompatibility and unique phys., elec., optical, and mech. properties of nanotubes provide the basis for new classes of materials for drug, protein, and gene delivery applications.
Journal of the American Chemical Society published new progress about 359860-27-8. 359860-27-8 belongs to imidazoles-derivatives, auxiliary class Other Aliphatic Heterocyclic,Chiral,Amine,Amide,Ether,Inhibitor, name is N-(2-(2-(2-(2-Aminoethoxy)ethoxy)ethoxy)ethyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide, and the molecular formula is C18H34N4O5S, Formula: C18H34N4O5S.
Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem