Month: November 2022

Synthesis of tri(indolyl)methanes mediated by acidic ionic liquid was written by Gu, Da-Gong;Ji, Shun-Jun. And the article was included in Chinese Journal of Chemistry in 2008.Category: imidazoles-derivatives The following contents are mentioned in the article:

Various tri(indolyl)methanes, e.g., I (R = H, Me, NO₂, PhCH₂O), were synthesized by condensation of indole and its derivatives with indole-3-carboxaldehydes using acidic ionic liquids [hmim]HSO₄/EtOH as an efficient and green catalyst system. This study involved multiple reactions and reactants, such as 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4Category: imidazoles-derivatives).

1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4) belongs to imidazole derivatives. Many natural products, especially alkaloids, contain the imidazole ring. These imidazoles share the 1,3-C3N2 ring but feature varied substituents. Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division.Category: imidazoles-derivatives

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Crystal structure of a diaqua-bis(3,5-di(1H-imidazol-1-yl)pyridine-κN)-bis(2-(4-carboxy-phenyl)acetato-κO]manganese(II), C₄₀H₃₆MnN₁₀O₁₀ was written by Ju, Feng-Yang;Guo, Wen-Bo;Li, Yun-Ping. And the article was included in Zeitschrift fuer Kristallographie – New Crystal Structures in 2017.Electric Literature of C11H9N5 The following contents are mentioned in the article:

C₄₀H₃₆MnN₁₀O₁₀, monoclinic, P2₁/c (number 14), a = 21.8966(12) Å, b = 7.2586(4) Å, c = 12.2346(6) Å, β = 98.232(1)°, V = 1924.52(18) ų, Z = 2, R_gt(F) = 0.0327, wR_ref(F²) = 0.0847, T = 296(2) K. This study involved multiple reactions and reactants, such as 3,5-Di(1H-imidazol-1-yl)pyridine (cas: 1374155-84-6Electric Literature of C11H9N5).

3,5-Di(1H-imidazol-1-yl)pyridine (cas: 1374155-84-6) belongs to imidazole derivatives. Many natural products, especially alkaloids, contain the imidazole ring. These imidazoles share the 1,3-C3N2 ring but feature varied substituents. Many drugs contain an imidazole ring, such as certain antifungal drugs, the nitroimidazole series of antibiotics, and the sedative midazolam.Electric Literature of C11H9N5

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Clauson Kaas pyrrole synthesis catalyzed by acidic ionic liquid under microwave irradiation was written by Aydogan, Feray;Yolacan, Cigdem. And the article was included in Journal of Chemistry in 2013.Application of 478935-29-4 The following contents are mentioned in the article:

A new procedure to synthesize N-substituted pyrroles by Clauson-Kaas reaction of amines with 2,5-dimethoxytetrahydrofuran catalyzed by acidic ionic liquid under microwave irradiation was developed. This procedure provides several advantages, such as high yield, clean product formation, and short reaction time. This study involved multiple reactions and reactants, such as 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4Application of 478935-29-4).

1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4) belongs to imidazole derivatives. Imidazole is a heterocyclic compound with a five-membered planar ring. It is amphoteric and highly polar. The pharmacophore of imidazole exists in bioactive compounds including amino acids, plant growth regulators and therapeutic agents.n increase of the alkyl chain length of the alcohols. Application of 478935-29-4

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Gastroprotective delivery of rabeprazole sodium along with metoclopramide hydrochloride using treated agar was written by Ratnakar, Raikar Prasiddhi;Pankaj, Gajare;Santoshi, Naik. And the article was included in International Journal of Pharmacy and Biological Sciences in 2021.Synthetic Route of C18H20N3NaO3S The following contents are mentioned in the article:

Particle engineering is a technique of phys. modification of the excipient at sub-particle level without altering chem. properties to achieve desired functionality. For development of immediate layer of Metoclopramide Hydrochloride Treated Agar was used as disintegrating agent and was compared with untreated agar. This study involved multiple reactions and reactants, such as Sodium 2-(((4-(3-methoxypropoxy)-3-methylpyridin-2-yl)methyl)sulfinyl)benzo[d]imidazol-1-ide (cas: 117976-90-6Synthetic Route of C18H20N3NaO3S).

Sodium 2-(((4-(3-methoxypropoxy)-3-methylpyridin-2-yl)methyl)sulfinyl)benzo[d]imidazol-1-ide (cas: 117976-90-6) belongs to imidazole derivatives. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole has become an important synthon in the development of new drugs. Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division.Synthetic Route of C18H20N3NaO3S

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Effects of cations and anions of ionic liquids on the production of 5-hydroxymethylfurfural from fructose was written by Shi, Chunyan;Zhao, Yuling;Xin, Jiayu;Wang, Jinquan;Lu, Xingmei;Zhang, Xiangping;Zhang, Suojiang. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2012.Safety of 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate The following contents are mentioned in the article:

Ionic liquids (ILs) with different cations and anions were used to study the effects on 5-hydroxymethylfurfural (HMF) preparation It was found that both aggregations of cations and hydrogen bonds of anions with fructose played important roles. Mol. dynamics simulations were also performed to explain the exptl. results. This study involved multiple reactions and reactants, such as 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4Safety of 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate).

1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4) belongs to imidazole derivatives. Imidazole derivatives generally have good solubility in protic solvents. Simple imidazole derivatives, such as 1H-imidazole, 2-methyl-1H-imidazole, and 1,2-dimethylimidazole, have very high solubility in water. Imidazole has been usedin the lysis, wash and elution buffer for the purification of histidine tagged Sonic Hedgehog(shh-N) protein, in elution buffer in stepwise gradient for the purification of histidine tagged aldo keto reductases using nickel affinity chromatography, as a component of homogenization buffer for the purification of phagosomal compartments from dendritic cells.Safety of 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Acidic ionic liquid-catalyzed highly efficient reaction of indoles to α,β-unsaturated ketones was written by Gu, Da-gong;Ji, Shun-jun;Wang, Hong-xia;Xu, Qiu-yan. And the article was included in Synthetic Communications in 2008.Recommanded Product: 478935-29-4 The following contents are mentioned in the article:

A novel method for the Michael reaction of indoles to α,β-unsaturated ketones catalyzed by acidic ionic liquid was reported. The authors obtained the corresponding products in excellent yields in the presence of [hmim]HSO₄. Development of this method resulted in a new protocol for the synthesis of β-indolylketones. This study involved multiple reactions and reactants, such as 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4Recommanded Product: 478935-29-4).

1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4) belongs to imidazole derivatives. Imidazole is the basic core of some natural products such as histidine, purine, histamine and DNA based structures, etc. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. The pharmacophore of imidazole exists in bioactive compounds including amino acids, plant growth regulators and therapeutic agents.n increase of the alkyl chain length of the alcohols. Recommanded Product: 478935-29-4

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

One-pot synthesis of 3,4-dihydropyrimidin-2(1H)-ones catalyzed by acidic ionic liquid was written by Ma, Jing-Jun;Zang, Xiao-Huan;Zhou, Xin;Wang, Chun;Li, Jing-Ci;Li, Qing. And the article was included in Indian Journal of Chemistry in 2007.Quality Control of 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate The following contents are mentioned in the article:

3,4-Dihydropyrimidin-2(1H)-ones were synthesized via one-pot reaction of aromatic aldehydes, Et acetoacetate and urea or thiourea catalyzed by room temperature ionic liquid [hmim]HSO₄. It was observed that the proposed method is fast, efficient and environmentally benign. The reaction time is 15 ∼ 55 min with the yields between 82 ∼ 97 %. This study involved multiple reactions and reactants, such as 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4Quality Control of 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate).

1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4) belongs to imidazole derivatives. Imidazole is the basic core of some natural products such as histidine, purine, histamine and DNA based structures, etc. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Many drugs contain an imidazole ring, such as certain antifungal drugs, the nitroimidazole series of antibiotics, and the sedative midazolam.Quality Control of 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Novel ionic liquid-mediated approach for the synthesis of tetracyclic[6,5,5,5]indole ring was written by Srivastava, Arjita;Siddiqui, Ibadur Rahman. And the article was included in Journal of Heterocyclic Chemistry in 2020.Formula: C10H20N2O4S The following contents are mentioned in the article:

A novel acidic ionic liquid-catalyzed protocol for the synthesis of diversely substituted tetracyclic indole core was devised. The application of ionic liquid provided this methodol. with various merits over conventional methods regarding reaction time, yield and ease of handling. Acidic ionic liquid was employed as a catalytic agent in this protocol. This study involved multiple reactions and reactants, such as 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4Formula: C10H20N2O4S).

1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4) belongs to imidazole derivatives. 1H-imidazole is an imidazole tautomer which has the migrating hydrogen at position 1. It is a conjugate base of an imidazolium cation. It is a conjugate acid of an imidazolide. It is a tautomer of a 4H-imidazole. Imidazole also acts as a microtubule destabilizing agents and inhibits topoisomerase and Cytochrome P450 Family 26 Subfamily A Member 1 (CYP26A1) enzymes.Formula: C10H20N2O4S

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

A novel preparation of thiazolo[5,4-c]pyridines and the synthesis of some imidazo[4,5-c]pyridines and oxazolo[4,5-c]pyridines was written by Katner, Allen S.;Brown, Raymond F.. And the article was included in Journal of Heterocyclic Chemistry in 1990.SDS of cas: 52538-09-7 The following contents are mentioned in the article:

Diethoxymethyl acetate was used to cyclize o-disubstituted aminopyridines to oxazolo [4,5-c]pyridines and imidazo[4,5-c]pyridines. All the possible imidazole-methylated imidazo[4,5-c]pyridines were prepared A novel synthesis of 2-substituted thiazolo[5,4-c]pyridines and 4-amino-3-pyridinethiol was discovered. This study involved multiple reactions and reactants, such as 2,3-Dimethyl-3H-imidazo[4,5-c]pyridine (cas: 52538-09-7SDS of cas: 52538-09-7).

2,3-Dimethyl-3H-imidazo[4,5-c]pyridine (cas: 52538-09-7) belongs to imidazole derivatives. The solubility of imidazoles in ethers is lower than that in alcohols and decreases with increasing chain length of the ethers . In contrast, the solubility of benzimidazoles in alcohols (C3–C6) is higher than in water and generally decreases with a Imidazole based anticancer drug find applications in cancer chemotherapy. It is used as buffer component for purification of the histidine tagged recombinant proteins in immobilized metal-affinity chromatography (IMAC).SDS of cas: 52538-09-7

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Study on the alkylation of isobutane/butene in acidic ionic liquids was written by Liu, Ying;Hu, Rui-sheng;Liu, Gui-li;Xu, Chun-ming. And the article was included in Fenzi Cuihua in 2010.SDS of cas: 478935-29-4 The following contents are mentioned in the article:

The catalytic performance of acidic ionic liquids on the isobutane/butene alkylation was investigated. The acidic strength of ionic liquids has been improved by modified cation, anion and liquid acid. The amount of TMP in the [MBSIM]OTf alkylate can reach 69.8%. The reaction system can be used for 8 times without significant decrease in catalytic performance. This study involved multiple reactions and reactants, such as 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4SDS of cas: 478935-29-4).

1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4) belongs to imidazole derivatives. 1H-imidazole is an imidazole tautomer which has the migrating hydrogen at position 1. It is a conjugate base of an imidazolium cation. It is a conjugate acid of an imidazolide. It is a tautomer of a 4H-imidazole. Imidazole based anticancer drug find applications in cancer chemotherapy. It is used as buffer component for purification of the histidine tagged recombinant proteins in immobilized metal-affinity chromatography (IMAC).SDS of cas: 478935-29-4

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem