Month: November 2022

Synthesis of N-(α-Alkoxyalkyl)benzotriazoles catalyzed by acidic ionic liquid at room temperature was written by Wang, Hong-Xia;Ji, Shun-Jun;Gu, Da-Gong. And the article was included in Chinese Journal of Chemistry in 2007.Recommanded Product: 478935-29-4 The following contents are mentioned in the article:

N-(α-Alkoxyalkyl)benzotriazoles were synthesized with ≤99% yield via the condensation of benzotriazole with various aldehydes and alcs. catalyzed by acidic ionic liquid [hmim]HSO₄ (hmim = 1-hexyl-3-methylimidazolium) at room temperature This novel method was effective when (EtO)₃CH was utilized instead of alcs. Moreover, acidic ionic liquid could be reused easily with no significant degradation of its catalytic activity. This study involved multiple reactions and reactants, such as 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4Recommanded Product: 478935-29-4).

1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4) belongs to imidazole derivatives. Imidazole derivatives generally have good solubility in protic solvents. Simple imidazole derivatives, such as 1H-imidazole, 2-methyl-1H-imidazole, and 1,2-dimethylimidazole, have very high solubility in water. Imidazole based anticancer drug find applications in cancer chemotherapy. It is used as buffer component for purification of the histidine tagged recombinant proteins in immobilized metal-affinity chromatography (IMAC).Recommanded Product: 478935-29-4

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Selective and efficient oxidation of sulfides to sulfoxides using ceric ammonium nitrate (CAN)/Bronsted acidic ionic liquid was written by Hajipour, Abdol R.;Khazdooz, Leila;Ruoho, Arnold E.. And the article was included in Phosphorus, Sulfur and Silicon and the Related Elements in 2009.COA of Formula: C10H20N2O4S The following contents are mentioned in the article:

A selective and efficient procedure for the oxidation of sulfides to the corresponding sulfoxides was reported using ceric ammonium nitrate in the presence of methylimidazolium hydrogen sulfate as Bronsted acidic ionic liquid ([Hmim]HSO₄) as the solvent under mild conditions. The use of nontoxic and inexpensive materials, straightforward procedure, short reaction times, and good yields of the products are the major advantages of this method. This study involved multiple reactions and reactants, such as 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4COA of Formula: C10H20N2O4S).

1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4) belongs to imidazole derivatives. The solubility of imidazoles in ethers is lower than that in alcohols and decreases with increasing chain length of the ethers . In contrast, the solubility of benzimidazoles in alcohols (C3–C6) is higher than in water and generally decreases with a Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division.COA of Formula: C10H20N2O4S

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

A direct method for the substitution of imidazo[1,5-a]pyridines at position 5 was written by Blatcher, Philip;Middlemiss, David. And the article was included in Tetrahedron Letters in 1980.Synthetic Route of C10H10N2O2 The following contents are mentioned in the article:

Lithiation of 3-ethylthioimidazo[1,5-a]pyridine (I; R = SEt, R¹ = H) (II) occurred at C-5. Quenching of this anion followed by desulfurization gave 5-substituted imidazo[1,5-a]pyridines. E.g. II reacted with BuLi and PhCHO giving 71% I [R = SEt, R¹ = CH(OH)Ph] which on treatment with Raney Ni gave 65% I [R = H, R¹ = CH(OH)Ph]. This study involved multiple reactions and reactants, such as Ethyl imidazo[1,5-a]pyridine-5-carboxylate (cas: 76292-67-6Synthetic Route of C10H10N2O2).

Ethyl imidazo[1,5-a]pyridine-5-carboxylate (cas: 76292-67-6) belongs to imidazole derivatives. Many natural products, especially alkaloids, contain the imidazole ring. These imidazoles share the 1,3-C3N2 ring but feature varied substituents. Imidazole has been usedin the lysis, wash and elution buffer for the purification of histidine tagged Sonic Hedgehog(shh-N) protein, in elution buffer in stepwise gradient for the purification of histidine tagged aldo keto reductases using nickel affinity chromatography, as a component of homogenization buffer for the purification of phagosomal compartments from dendritic cells.Synthetic Route of C10H10N2O2

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Chitosan/ionic liquid forms a renewable and reusable catalyst system used for the synthesis of highly functionalized spiro derivatives was written by Rai, Pratibha;Srivastava, Madhulika;Singh, Jaya;Singh, Jagdamba. And the article was included in New Journal of Chemistry in 2014.HPLC of Formula: 478935-29-4 The following contents are mentioned in the article:

Chitosan, a reusable heterogeneous catalyst, can be combined with an ionic liquid as a green solvent to generate a highly efficient catalyst system for densely functionalized and diversified target mol. The reaction is completed with a good to excellent yield. This procedure demonstrates an eco-friendly catalyst system and eliminates the use of toxic transition metal catalysts, bases and volatile organic solvents, which adversely affect the environment and human beings. This study involved multiple reactions and reactants, such as 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4HPLC of Formula: 478935-29-4).

1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4) belongs to imidazole derivatives. Many natural products, especially alkaloids, contain the imidazole ring. These imidazoles share the 1,3-C3N2 ring but feature varied substituents. Imidazole also acts as a microtubule destabilizing agents and inhibits topoisomerase and Cytochrome P450 Family 26 Subfamily A Member 1 (CYP26A1) enzymes.HPLC of Formula: 478935-29-4

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Bis(arylimidazole) Iridium Picolinate Emitters and Preferential Dipole Orientation in Films was written by Huckaba, Aron J.;Senes, Alessia;Aghazada, Sadig;Babaei, Azin;Meskers, Stefan C. J.;Zimmermann, Iwan;Schouwink, Pascal;Gasilova, Natalia;Janssen, Rene A. J.;Bolink, Henk J.;Nazeeruddin, Mohammad Khaja. And the article was included in ACS Omega in 2018.Product Details of 914306-50-6 The following contents are mentioned in the article:

The straightforward synthesis and photophys. properties of a new series of heteroleptic iridium(III) bis(2-arylimidazole) picolinate complexes are reported. Each complex has been characterized by NMR, UV-vis, cyclic voltammetry, and photoluminescent angle dependency, and the emissive properties of each are described. The preferred orientation of transition dipoles in emitter/host thin films indicated more preferred orientation than homoleptic complex Ir(ppy)₃. This study involved multiple reactions and reactants, such as 1-(2,6-Diisopropylphenyl)-2-phenyl-1H-imidazole (cas: 914306-50-6Product Details of 914306-50-6).

1-(2,6-Diisopropylphenyl)-2-phenyl-1H-imidazole (cas: 914306-50-6) belongs to imidazole derivatives. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole has become an important synthon in the development of new drugs. Imidazole based anticancer drug find applications in cancer chemotherapy. It is used as buffer component for purification of the histidine tagged recombinant proteins in immobilized metal-affinity chromatography (IMAC).Product Details of 914306-50-6

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Acid-induced chemoselective arylthiolations of electron-rich arenes in ionic liquids from sodium arylsulfinates: the reducibility of halide anions in [Hmim]Br was written by Xu, Zhu-bing;Lu, Guo-ping;Cai, Chun. And the article was included in Organic & Biomolecular Chemistry in 2017.Related Products of 478935-29-4 The following contents are mentioned in the article:

An acid-induced protocol for the chemoselective arylthiolations of electron-rich arenes in ionic liquids from sodium arylsulfinates is introduced. The chem., in which [Hmim]Br (heaxylmethylimidazolium bromide) is used as both a solvent and a reducer, provides several advantages including odorless and simple operation, inexpensive reagents, recyclable solvents and gram-scale synthesis. This study involved multiple reactions and reactants, such as 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4Related Products of 478935-29-4).

1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4) belongs to imidazole derivatives. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole has become an important synthon in the development of new drugs. Imidazole based anticancer drug find applications in cancer chemotherapy. It is used as buffer component for purification of the histidine tagged recombinant proteins in immobilized metal-affinity chromatography (IMAC).Related Products of 478935-29-4

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

The discovery of fluazaindolizine: A new product for the control of plant parasitic nematodes was written by Lahm, George P.;Desaeger, Johan;Smith, Ben K.;Pahutski, Thomas F.;Rivera, Michel A.;Meloro, Tony;Kucharczyk, Roman;Lett, Renee M.;Daly, Anne;Smith, Brenton T.;Cordova, Daniel;Thoden, Tim;Wiles, John A.. And the article was included in Bioorganic & Medicinal Chemistry Letters in 2017.Quality Control of Ethyl 8-chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridine-2-carboxylate The following contents are mentioned in the article:

Fluazaindolizine is a new highly effective and selective product for the control of plant parasitic nematodes. Specificity for nematodes coupled with absence of activity against the target sites of com. nematicides suggests that fluazaindolizine has a novel mode of action. The discovery, structure-activity development and biol. properties for this new class of nematicides are presented. This study involved multiple reactions and reactants, such as Ethyl 8-chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridine-2-carboxylate (cas: 353258-31-8Quality Control of Ethyl 8-chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridine-2-carboxylate).

Ethyl 8-chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridine-2-carboxylate (cas: 353258-31-8) belongs to imidazole derivatives. Imidazole derivatives generally have good solubility in protic solvents. Simple imidazole derivatives, such as 1H-imidazole, 2-methyl-1H-imidazole, and 1,2-dimethylimidazole, have very high solubility in water. Imidazole has been usedin the lysis, wash and elution buffer for the purification of histidine tagged Sonic Hedgehog(shh-N) protein, in elution buffer in stepwise gradient for the purification of histidine tagged aldo keto reductases using nickel affinity chromatography, as a component of homogenization buffer for the purification of phagosomal compartments from dendritic cells.Quality Control of Ethyl 8-chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridine-2-carboxylate

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Synthesis of 1-(2,6-diisopropylphenyl)-2-phenyl-1H-imidazole was written by Zhou, Lin-bo;Lu, Meng-meng;Xing, Lei;Chen, Guo-liang. And the article was included in Jingxi Huagong Zhongjianti in 2015.Recommanded Product: 914306-50-6 The following contents are mentioned in the article:

The target compound 1-(2,6-diisopropylphenyl)-2-phenyl-1H-imidazole was prepared in overall yield of 47.69% starting from 2,6-diisopropyl aniline via acylation by benzoyl chloride, chlorination by phosphorus oxychloride, nucleophilic substitution by aminoacetaldehyde di-Et acetal and cyclization by phosphate. The structure of target compound was characterized by ¹H NMR and ESI-MS. This study involved multiple reactions and reactants, such as 1-(2,6-Diisopropylphenyl)-2-phenyl-1H-imidazole (cas: 914306-50-6Recommanded Product: 914306-50-6).

1-(2,6-Diisopropylphenyl)-2-phenyl-1H-imidazole (cas: 914306-50-6) belongs to imidazole derivatives. Many natural products, especially alkaloids, contain the imidazole ring. These imidazoles share the 1,3-C3N2 ring but feature varied substituents. This ring system is present in important biological building blocks, such as histidine and the related hormone histamine.Recommanded Product: 914306-50-6

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Transition-metal-free regioselective C-H halogenation of imidazo[1,2-a]pyridines: sodium chlorite/bromite as the halogen source was written by Li, Junxuan;Tang, Jiayi;Wu, Yuanheng;He, Qiuxing;Yu, Yue. And the article was included in RSC Advances in 2018.SDS of cas: 866135-66-2 The following contents are mentioned in the article:

A facile transition-metal-free regioselective halogenation of imidazo[1,2-a]pyridines using sodium chlorite/bromite as the halogen source is presented. The reaction has provided an efficient method for the formation of C-Cl or C-Br bonds to synthesize 3-chloro or 3-bromo-imidazo[1,2-a]pyridines which were then efficiently transformed into imidazo[1,2-a]pyridine core π-systems by Suzuki-Miyaura reactions. This study involved multiple reactions and reactants, such as 3-Bromo-8-methylimidazo[1,2-a]pyridine (cas: 866135-66-2SDS of cas: 866135-66-2).

3-Bromo-8-methylimidazo[1,2-a]pyridine (cas: 866135-66-2) belongs to imidazole derivatives. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole has become an important synthon in the development of new drugs. Imidazole has been usedin the lysis, wash and elution buffer for the purification of histidine tagged Sonic Hedgehog(shh-N) protein, in elution buffer in stepwise gradient for the purification of histidine tagged aldo keto reductases using nickel affinity chromatography, as a component of homogenization buffer for the purification of phagosomal compartments from dendritic cells.SDS of cas: 866135-66-2

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem