Zhang, C. published the artcileEfficient synthesis and biological activity of novel indole derivatives as VEGFR-2 tyrosine kinase inhibitors, SDS of cas: 4760-35-4, the publication is Russian Journal of General Chemistry (2017), 87(12), 3006-3016, database is CAplus.
Series of novel indole derivatives, e.g. I were synthesized as potent inhibitors for the vascular endothelial growth factor receptor 2 (VEGFR-2) tyrosine kinase. Among those, compound I demonstrated the highest growth inhibition rate of 66.7% against the VEGFR-2 tyrosine kinase at 10 μM which indicates that indole-benzothiazole might be the favorable structure. The binding mode of compound I with VEGFR-2 tyrosine kinase was evaluated by mol. docking.
Russian Journal of General Chemistry published new progress about 4760-35-4. 4760-35-4 belongs to imidazoles-derivatives, auxiliary class Chloride,Benzimidazole, name is 2-(Chloromethyl)-1-methyl-1H-benzo[d]imidazole, and the molecular formula is C3H9ClOS, SDS of cas: 4760-35-4.
Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem