Chi, Young Shik published the artcileAsymmetrically functionalized, four-armed, poly(ethylene glycol) compounds for construction of chemically functionalizable non-biofouling surfaces, Synthetic Route of 359860-27-8, the publication is Chemistry – An Asian Journal (2009), 4(1), 135-142, database is CAplus and MEDLINE.
Asym. functionalized, four-armed, Tween20 derivatives that formed stable monomol. films on solid substrates were designed and synthesized. Thiol-modified Tween20 was used for forming self-assembled monolayers (SAMs) on gold, and maleimide-modified Tween20 was introduced onto SiO2 surfaces with SAMs of (3-mercaptopropyl)trimethoxysilane through Michael addition These structurally modified Tween20 compounds gave the original characteristics of Tween20, non-biofouling (from ethylene glycol groups) and functionalizable (from OH groups) properties, to each substrate. The non-biofouling properties of the Tween20-coated gold and SiO2 surfaces were investigated by surface plasmon resonance spectroscopy and ellipsometry, and these surfaces showed strong resistance against nonspecific adsorption of proteins. In addition, the biospecific binding of streptavidin was achieved after coupling of (+)-biotinyl-3,6,9-trioxaundecanediamine onto the non-biofouling surfaces through amide-bond formation.
Chemistry – An Asian Journal published new progress about 359860-27-8. 359860-27-8 belongs to imidazoles-derivatives, auxiliary class Other Aliphatic Heterocyclic,Chiral,Amine,Amide,Ether,Inhibitor, name is N-(2-(2-(2-(2-Aminoethoxy)ethoxy)ethoxy)ethyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide, and the molecular formula is C18H34N4O5S, Synthetic Route of 359860-27-8.
Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem