Halogen migration in reactions of halo imidazoles with potassium amide in liquid ammonia was written by De Bie, D. A.;Van der Plas, H. C.. And the article was included in Recueil des Travaux Chimiques des Pays-Bas in 1969.Category: imidazoles-derivatives This article mentions the following:
5-Bromo-1-methylimidazole (I) is treated with KNH2 to give a mixture of 4-bromo-1-methylimidazole (II) and 1-methylimidazole (III). A mixture of 4,5-dibromo-1-methylimidazole and III gives II. In the experiment, the researchers used many compounds, for example, 4-Bromo-1-methylimidazole (cas: 25676-75-9Category: imidazoles-derivatives).
4-Bromo-1-methylimidazole (cas: 25676-75-9) belongs to imidazole derivatives. Imidazole derivatives generally have good solubility in protic solvents. Simple imidazole derivatives, such as 1H-imidazole, 2-methyl-1H-imidazole, and 1,2-dimethylimidazole, have very high solubility in water. Imidazole based anticancer drug find applications in cancer chemotherapy. It is used as buffer component for purification of the histidine tagged recombinant proteins in immobilized metal-affinity chromatography (IMAC).Category: imidazoles-derivatives
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem