Regio- and stereocontrolled synthesis and conformational analysis of benzimidazole nucleosides was written by Ji, Qi;Li, Jinliang;Ding, Fei;Han, Jie;Pang, Meili;Liu, Shuangxi;Meng, Jiben. And the article was included in Tetrahedron in 2006.SDS of cas: 4887-83-6 This article mentions the following:
Regio- and stereocontrolled synthesis and conformational anal. of a series of benzimidazole nucleosides were achieved. A simple method by 1H NMR 1D NOE experiment was developed for estimation of syn or anti conformation of benzimidazole nucleosides. Substituents at C2 of benzimidazole demonstrated to play a key role both in the unexpected regioselectivity of the glycosidic reaction and in the conformation distributions of the final products. In the experiment, the researchers used many compounds, for example, 7-Methyl-1H-benzo[d]imidazole (cas: 4887-83-6SDS of cas: 4887-83-6).
7-Methyl-1H-benzo[d]imidazole (cas: 4887-83-6) belongs to imidazole derivatives. Imidazole is the basic core of some natural products such as histidine, purine, histamine and DNA based structures, etc. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole also acts as a microtubule destabilizing agents and inhibits topoisomerase and Cytochrome P450 Family 26 Subfamily A Member 1 (CYP26A1) enzymes.SDS of cas: 4887-83-6
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem