Asymmetric Synthesis of Multi-Substituted Tetrahydrofurans via Palladium/Rhodium Synergistic Catalyzed [3+2] Decarboxylative Cycloaddition of Vinylethylene Carbonates was written by Ming, Siliang;Qurban, Saira;Du, Yu;Su, Weiping. And the article was included in Chemistry – A European Journal in 2021.Related Products of 85692-37-1 This article mentions the following:
An efficient synergistic catalysis for the diastereo- and enantioselective synthesis of multi-substituted THF derivatives I (R1 = Me, i-Pr, Ph; R2 = Ph, thiophen-2-yl, naphthalen-2-yl, etc.; R3 = Ph, 4-chloropheny, furan-2-yl, etc.) has been developed. Under mild reaction conditions, a series of target mols. with three consecutive stereocenters were synthesized by a palladium(0)/rhodium(III) bimetal-catalyzed asym. decarboxylative [3+2]-cycloaddition of vinylethylene carbonates II with α,β-unsaturated carbonyl compds III. The corresponding adducts were obtained with moderate to high yields (67% ∼ 98%) and excellent stereoselectivities (>20:1 d.r., up to 99% ee). In the experiment, the researchers used many compounds, for example, 1-(1-Methyl-1H-imidazol-2-yl)ethanone (cas: 85692-37-1Related Products of 85692-37-1).
1-(1-Methyl-1H-imidazol-2-yl)ethanone (cas: 85692-37-1) belongs to imidazole derivatives. Imidazole is a heterocyclic compound with a five-membered planar ring. It is amphoteric and highly polar. Imidazole has been usedin the lysis, wash and elution buffer for the purification of histidine tagged Sonic Hedgehog(shh-N) protein, in elution buffer in stepwise gradient for the purification of histidine tagged aldo keto reductases using nickel affinity chromatography, as a component of homogenization buffer for the purification of phagosomal compartments from dendritic cells.Related Products of 85692-37-1
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem