Ionic liquid in thin-layer chromatography of anionic surfactants: selective separation of sodium deoxycholate and identification in commercial products was written by Mohammad, Ali;Mobin, Rizwana. And the article was included in Tenside, Surfactants, Detergents in 2015.Application In Synthesis of 1-Methyl-1H-imidazol-3-ium chloride This article mentions the following:
The coupling of a silica static flat phase impregnated with an ionic liquid (1-methylimidazolium chloride) as stationary phase with 2-methyltetrahydrofuran an alternative green solvent of THF as mobile phase has been very successful for a selective separation of sodium deoxycholate from other commonly used anionic surfactants. The proposed thin-layer chromatog. system is capable to anal. discriminate among the anionic surfactants in relation to their migration behavior on an ionic liquid loaded silica layer. The surface structure and chem. composition of silica gel G modified by impregnation were examined with the aid of SEM (SEM) and energy dispersive X-ray spectrophotometry (EDX) resp. Effects of concentration level of 1-Me imidazolium chloride as impregnant and its substitution by other ionic liquids (1,2,3-trimethylimidazolium Me sulfate, 1-ethyl-3-methylimidazolium tetrafluoroborate) were also studied to decide the optimum exptl. conditions for better separation possibilities. Chromatog. parameters such as ΔRF, the separation factor (α) and the resolution (RS) for the separation and limit of detection were calculated The developed method has been usefully applied for the identification of sodium deoxycholate and sodium lauryl sulfate in formulated and com. available products (Colgate toothpaste and Head & Shoulder Shampoo). In the experiment, the researchers used many compounds, for example, 1-Methyl-1H-imidazol-3-ium chloride (cas: 35487-17-3Application In Synthesis of 1-Methyl-1H-imidazol-3-ium chloride).
1-Methyl-1H-imidazol-3-ium chloride (cas: 35487-17-3) belongs to imidazole derivatives. The solubility of imidazoles in ethers is lower than that in alcohols and decreases with increasing chain length of the ethers . In contrast, the solubility of benzimidazoles in alcohols (C3–C6) is higher than in water and generally decreases with a Imidazole based anticancer drug find applications in cancer chemotherapy. It is used as buffer component for purification of the histidine tagged recombinant proteins in immobilized metal-affinity chromatography (IMAC).Application In Synthesis of 1-Methyl-1H-imidazol-3-ium chloride
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem